Genetic characterization of Toxoplasma gondii in women of reproductive age in the north of Iran

Bahman Rahimi‑Esboei; Mohammad Taghi Rahimi; Abozar Ghorbani; Seifali Mahdavi

doi:10.4103/jnms.jnms_104_20

Journal of Nursing and Midwifery Sciences

The Official Journal of Mazandaran University of Medical Sciences

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https://doi.org/10.4103/jnms.jnms_104_20

Genetic characterization of Toxoplasma gondii in women of reproductive age in the north of Iran

Author(s):

Bahman Rahimi‑Esboei^{1, 2},

Mohammad Taghi Rahimi³,

Abozar Ghorbani²,

Seifali Mahdavi^4,*

1Department of Microbiology, School of Medicine, Islamic Azad University, Tonekabon Branch, Tonekabon

2Toxoplasma Research Center, School of Medicine, Mazandaran University of Medical Sciences

3Center for Health‑Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran

44Department of Paramedical, Amol Faculty of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari

Journal of Nursing and Midwifery Sciences:Vol. 8, issue 2; 74-78

Published online:May 04, 2021

Article type:Research Article

Received:Aug 04, 2020

Accepted:Dec 15, 2020

How to Cite:Bahman Rahimi‑EsboeiMohammad Taghi RahimiAbozar GhorbaniSeifali MahdaviGenetic characterization of Toxoplasma gondii in women of reproductive age in the north of Iran.J Nurs Midwifery Sci.8(2):e140754.https://doi.org/10.4103/jnms.jnms_104_20.

Abstract

Context: Toxoplasmosis in females plays a prominent role in fetal health owing to serious pathological problems including abortion, hydrocephaly, mental retardation, and chorioretinitis.
Aims: The purpose of the present investigation was to study the seroprevalence and genetic characterization of Toxoplasma gondii in female population using ELISA and polymerase chain reaction (PCR) techniques in Mazandaran Province, Iran.
Setting and Design: This was a cross‑sectional study on girls and women of childbearing age in Mazandaran Province from 2018 to 2019.
Materials and Methods: A total of 500 serum samples were collected and studied employing ELISA and PCR assays. Prior to sampling, a questionnaire was filled out for each case.
Statistical Analysis Used: Chi‑square or Fisher’s exact test was used to analyze the obtained data, and associations were considered statistically significant at P < 0.05.
Results: The total seroprevalence of the studied sera was 26.6% for IgG antibody, and also, 4.2% of the samples showed anti‑Toxoplasma IgM antibody. Furthermore, there was a statistically significant relationship between seroprevalence of Toxoplasma and residential area and marital status. Genetic characterization of T. gondii revealed that 20% of the positive samples were Type II and 0.2% was Types I and II.
Conclusions: The seroprevalence of toxoplasmosis in girls and women of childbearing age in the north of Iran is considerable. Residential area and consumption of vegetables are identified as potentially preventable risk factors for acquiring toxoplasmosis in Mazandaran Province.

Keywords

Antibody

Genotyping

Polymerase chain reaction

Seroprevalence

Toxoplasma gondii

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Author(s):

Bahman Rahimi‑Esboei:[PubMed][Scholar]
Mohammad Taghi Rahimi:[PubMed][Scholar]
Abozar Ghorbani:[PubMed][Scholar]
Seifali Mahdavi:[PubMed][Scholar]