The effect of natural products use on blood pressure in Iran: Systematic review and meta-analysis

Moloud Fakhri; Alireza  Fatahian; Seyede‑Sedigheh Yousefi; Mahmood Moosazadeh; Mohammad Azadbakht

doi:10.4103/jnms.jnms_74_21

Journal of Nursing and Midwifery Sciences

The Official Journal of Mazandaran University of Medical Sciences

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https://doi.org/10.4103/jnms.jnms_74_21

The effect of natural products use on blood pressure in Iran: Systematic review and meta-analysis

Author(s):

Moloud Fakhri^{1, 2,*},

Alireza Fatahian^3,**,

Seyede‑Sedigheh Yousefi¹,

Mahmood Moosazadeh⁴,

Mohammad Azadbakht

^{1, 5}

1Traditional and Complementary Medicine Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran

2World Federation of Acupuncture-Moxibustion Societies (WFAS), Beijing, China

3Interventional Electrophysiologist, Assistant Professor of Cardiology, Cardiovascular Research Center, Mazandaran University of Medical Sciences

4Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences

5Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran

Corresponding Authors:

Journal of Nursing and Midwifery Sciences:Vol. 9, issue 2; 152-165

Published online:Jun 10, 2022

Article type:Review Article

Received:May 16, 2021

Accepted:Feb 16, 2022

How to Cite:Moloud FakhriAlireza FatahianSeyede‑Sedigheh YousefiMahmood MoosazadehMohammad AzadbakhtThe effect of natural products use on blood pressure in Iran: Systematic review and meta-analysis.J Nurs Midwifery Sci.9(2):e141426.https://doi.org/10.4103/jnms.jnms_74_21.

Abstract

Context: Hypertension (HTN) is the leading risk factor for mortality worldwide. People tend to seek traditional therapies since chemical medicines have various side effects and high costs.
Aims: Therefore, the present study investigated the effect of natural products on blood pressure in Iran by meta‑analysis.
Materials and Methods: In this meta‑analysis, those initial studies were included that were randomized clinical trials with or without blinded and studies with quasi‑experimental design. The national and international databases included Barekat Gostar, SID, Magiran, IranDoc, PubMed, Scopus, Web of Science, Cochrane, and Google Scholar by keywords: natural products, medicinal plants, herbal medicines, pharmaceutical plant, blood pressure, hypertension, Iran.
Statistical Analysis Used: The gathered data were analyzed in STATA ver. 14.
Results: In 76 studies with a sample size of 2886 subjects, 60 types of natural products were used to reduce blood pressure. The most to the least effective natural products for systolic blood pressure (SBP) were the mixture of garlic and lemon juice, barberry, sour tea, barberry juice, cumin powder, resveratrol, garlic, olive leaf, orange juice, artichoke, flaxseed, saffron, Berberis vulgaris + apple vinegar, and lemon, respectively. Considering the natural products reducing diastolic blood pressure (DBP), the most to the least effective natural products were the mixture of garlic and lemon juice, sour tea, olive leaf, saffron, and olive oil, respectively.
Conclusion: Based on the results, the mixture of garlic and lemon juice had the greatest effect on reducing both SBP and DBP levels. It was also found out that its effect was slightly greater in decreasing the SBP than the DBP.

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Author(s):

Moloud Fakhri:[PubMed][Scholar]
Alireza Fatahian:[PubMed][Scholar]
Seyede‑Sedigheh Yousefi:[PubMed][Scholar]
Mahmood Moosazadeh:[PubMed][Scholar]
Mohammad Azadbakht:[PubMed][Scholar]