Correlation between the protein content in 6-hours and 24-hours urine samples in hospitalized women with probable preeclampsia

authors:

avatar Sanam Moradan , * , avatar mojghan rahmanian , avatar raheb Ghorbani

Koomesh: Vol.17, issue 1; 54-59
article type: issue_documents_importer
received: February 02, 2014
accepted: August 08, 2015

how to cite: Moradan S, rahmanian M, Ghorbani R. Correlation between the protein content in 6-hours and 24-hours urine samples in hospitalized women with probable preeclampsia. koomesh. 2015;17(1):e150766. 

Abstract

 Introduction: Preeclampsia is one of the most important complications during pregnancy and the gold standard for its diagnosis is 24 hours urine protein assay. In relation to that, the aim of the present study was to determine the possibility of replacing 6-hours with 24-hours urine protein assay. Materials and Methods: A descriptive analytic study was performed on 30 pregnant women over 20 weeks of gestation, hospitalized with probable diagnosis of preeclampsia with at least a positive urinary strip test or (1+) for protein and blood presure ≥140/90. First a random urine sample was obtained for measuring protein/ creatinine ratio. Then 2 distinctive sets of urine samples were collected: first for 6-hours and then for 18-hours. Protein was measured in the 6 hour sample, then two samples were mixed and after the protein assay the concentration was counted as the protein content in 24-hours sample. Data was analyzed by Spearman correlation with considering P-value (