Body composition and anthropometric indices in pre- and postmenopausal women with breast cancer

authors:

avatar Fatemeh Ameri , avatar Mohammad Esmaeil Akbari , avatar Morteza Abdollahi , avatar Marjan Ajami , avatar Sayed Hosein Davoodi ORCID , *

Koomesh: Vol.19, issue 2; 341-352
published online: June 09, 2017
article type: Research Article
received: April 02, 2016
accepted: January 09, 2017

how to cite: Ameri F, Akbari M E, Abdollahi M, Ajami M, Davoodi S H. Body composition and anthropometric indices in pre- and postmenopausal women with breast cancer. koomesh. 2017;19(2):e151087. 

Abstract

Introduction: Breast cancer is the second most common cancer worldwide and the most common cancer among women and notably the fourth leading cause of death worldwide. Overweight and obesity are two main risk factors which have been proven the creation of breast cancer after menopause. Therefore, this study aimed to investigate the relationship between anthropometric and body composition in pre-menopausal and post-menopausal breast cancer risk. Materials and Methods: In this case-control study, 88 patients with breast cancer (n = 48 pre-menopausal and post-menopausal 41) and 86 controls (45 premenopausal and 41 postmenopausal) who were matched by age, studied respectively. The cases, women who were admitted to Shohada Hospital recently diagnosed with breast cancer and had not chemotherapy or radiation therapy. The controls of women who were admitted to the same hospital had no history of any type of cancer or hormonal disease. The subjects were studied anthropometric indices and body composition was also measured by tanita Body Composition analyzer. For analysis the findings, chi-square and logistic regression was used. Results: In the study of case and control groups separately menopausal status, in pre-menopausal population, overweight women (BMI=24/91-29/9kg/m2) had lower odds ratio of developing breast cancer (OR=0/23 CI=0/84-0/06). In postmenopausal population with waist-to-hip ratio (0/80-0/84), WHR was significantly associated with breast cancer risk (OR=0/09 CI=0/60-0/02). Conclusion: In this study, premenopausal overweight women had lower odds ratio of developing breast cancer. High WHR was associated with breast cancer risk in postmenopausal women.

References

  • 1.

    Jamshidi Naeini Y, Esmaeili S, Akbari ME, Davoodi H. Iron deficiency and overload and its association with cancer risk in humans: A review. Koomesh 2015; 16: 289-300. (Persian).

  • 2.

    Jamshidinaeini Y, Akbari ME, Abdollahi M, Ajami M, Davoodi SH. Vitamin D status and risk of breast cancer in Iranian women: A case-control study. J Am Coll Nutr 2016; 22: 1-8.

  • 3.

    Hosseinzadeh M, Eivazi Ziaei J, Mahdavi N, Aghajari P, Vahidi M, Fateh A, Asghari E. Risk factors for breast cancer in Iranian women: a hospital-based case-control study in tabriz, iran. J Breast Cancer 2014; 17: 236-243.

  • 4.

    Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917.

  • 5.

    Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.

  • 6.

    Bray F, Ren JS, Masuyer E, Ferlay J. Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer 2013; 132: 1133-1145.

  • 7.

    Tahergurabi Z, Moadi M, Mesbahzade B. Breast cancer, a preventive deasese. Med Univ Birjand 2014; 21: 141-126.

  • 8.

    Anothaisintawee T, Wiratkapun C, Lerdsitthichai P, Kasamesup V, Wongwaisayawan S, Srinakarin J, et al. Risk factors of breast cancer a systematic review and meta-analysis. Asia Pac J Public Health 2013; 25: 368-387.

  • 9.

    Assi N, Moskal A, Slimani N, Viallon V, Chajes V, Freisling H, et al. A treelet transform analysis to relate nutrient patterns to the risk of hormonal receptor-defined breast cancer in the european prospective investigation into cancer and nutrition (EPIC). Public Health Nutr 2016; 19: 242-254.

  • 10.

    McKenzie F, Ellison-Loschmann L, Jeffreys M, Firestone R, Pearce N, Romieu I. Cigarette smoking and risk of breast cancer in a New Zealand multi-ethnic case-control study. PloS One 2013; 8: e63132.

  • 11.

    Porter P. Westernizing women's risks? Breast cancer in lower-income countries. N Engl J Med 2008; 358: 213-216.

  • 12.

    McCullough LE, Eng SM, Bradshaw PT, Cleveland RJ, Teitelbaum SL, Neugut AI, Gammon MD. Fat or fit: the joint effects of physical activity, weight gain, and body size on breast cancer risk. Cancer 2012; 118: 4860-4868.

  • 13.

    Roohparvarzade N. Prevalence of risk factors for breast cancer in women (20 to 69 Years old) in Isfahan 2012-2013. Iran J Breast Dis 2014; 7: 52-61.

  • 14.

    Rahnama N, Nouri R, Rahmaninia F, Damirchi A, Emami H. The effects of exercise training on maximum aerobic capacity, resting heart rate, blood pressure and anthropometric variables of postmenopausal women with breast cancer. J Res Med Sci 2010; 15: 78-83.

  • 15.

    Rohan TE, Heo M, Choi L, Datta M, Freudenheim JL, Kamensky V, et al. Body fat and breast cancer risk in postmenopausal women: a longitudinal study. J Cancer Epidemiol 2013; 2013: 754815.

  • 16.

    Sonnenschein E, Toniolo P, Terry MB, Bruning PF, Kato I, Koenig KL, Shore RE. Body fat distribution and obesity in pre-and postmenopausal breast cancer. Int J Epidemiol 1999; 28: 1026-1031.

  • 17.

    Amadou A, Hainaut P, Romieu I. Role of obesity in the risk of breast cancer: lessons from anthropometry. J Oncol 2013; 2013: 906495.

  • 18.

    Ogundiran TO, Huo D, Adenipekun A, Campbell O, Oyesegun R, Akang E, et al. Body fat distribution and breast cancer risk: findings from the Nigerian breast cancer study. Cancer Causes Control 2012; 23: 565-574.

  • 19.

    Ray A, Cleary MP. Obesity and breast cancer: a clinical biochemistry perspective. Clin Biochem 2012; 45: 189-197.

  • 20.

    Onsory K, Ranapoor S. Breast cancer and the effect of environmental factors involved. N Cell Mol Biotechnol J 2011; 1: 59-70.

  • 21.

    Montazeri A, Sadighi J, Farzadi F, Maftoon F, Vahdaninia M, Ansari M, et al. Weight, height, body mass index and risk of breast cancer in postmenopausal women: a case-control study. BMC Cancer 2008; 8: 278.

  • 22.

    Wang XL, Jia CX, Liu LY, Zhang Q, Li YY, Li L. Obesity, diabetes mellitus, and the risk of female breast cancer in Eastern China. World J Surg Oncol 2013; 11: 71.

  • 23.

    de Vasconcelos AB, Azevedo e Silva Mendonca G, Sichieri R. Height, weight, weight change and risk of breast cancer in Rio de Janeiro, Brazil. Sao Paulo Med J 2001; 119: 62-69.

  • 24.

    Palmer JR, Rao RS, Adams-Campbell LL, Rosenberg L. Height and breast cancer risk: results from the black women's health study (United States). Cancer Causes Control 2001; 12: 343-348.

  • 25.

    Friedenreich CM. Review of anthropometric factors and breast cancer risk. Eur J Cancer Prev 2001; 10: 15-32.

  • 26.

    Lovegrove JA. Obesity, body fat distribution and breast cancer. Nutr Res Rev 2002; 15: 389-412.

  • 27.

    Baer HJ, Rich-Edwards JW, Colditz GA, Hunter DJ, Willett WC, Michels KB. Adult height, age at attained height, and incidence of breast cancer in premenopausal women. Int J Cancer 2006; 119: 2231-2235.

  • 28.

    van den Brandt PA, Spiegelman D, Yaun SS, Adami HO, Beeson L, Folsom AR, et al. Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk. Am J Epidemiol 2000; 152: 514-527.

  • 29.

    Berstad P, Coates RJ, Bernstein L, Folger SG, Malone KE, Marchbanks PA, et al. A case-control study of body mass index and breast cancer risk in white and African-American women. Cancer Epidemiol Biomarkers Prev 2010; 19: 1532-1544.

  • 30.

    Amadou A, Ferrari P, Muwonge R, Moskal A, Biessy C, Romieu I, Hainaut P. Overweight, obesity and risk of premenopausal breast cancer according to ethnicity: a systematic review and dose-response meta-analysis. Obes Rev 2013; 14: 665-678.

  • 31.

    Shokoohi M, Ali K, Siyasi F, Reza M. Study of association between anthropometric indices and breast cancer in women referring to Imam Khomeini hospital Breast diseases iran 2009; 3. (Persian).

  • 32.

    Cheraghi Z, Poorolajal J, Hashem T, Esmailnasab N, Doosti Irani A. Effect of body mass index on breast cancer during premenopausal and postmenopausal periods: a meta-analysis. PloS One 2012; 7: e51446.

  • 33.

    Guth U, Schmid S, Eichholzer M. [Development of overweight and obesity in breast cancer patients and its significance for diagnosis and clinical management: results of the basel breast cancer database 1990-2009]. Praxis 2013; 102: 473-480.

  • 34.

    Carpenter CL, Ross RK, Paganini-Hill A, Bernstein L. Effect of family history, obesity and exercise on breast cancer risk among postmenopausal women. Int J Cancer 2003; 106: 96-102.

  • 35.

    Torio CM, Klassen AC, Curriero FC, Caballero B, Helzlsouer K. The modifying effect of social class on the relationship between body mass index and breast cancer incidence. Am J Publ Health 2010; 100: 146-151.

  • 36.

    Wada K, Nagata C, Tamakoshi A, Matsuo K, Oze I, Wakai K, et al. Body mass index and breast cancer risk in Japan: a pooled analysis of eight population-based cohort studies. Ann Oncol 2014; 25: 519-524.

  • 37.

    Abrahamson PE, Gammon MD, Lund MJ, Flagg EW, Porter PL, Stevens J, et al. General and abdominal obesity and survival among young women with breast cancer. Cancer Epidemiol Biomarkers Prev 2006; 15: 1871-1877.

  • 38.

    Green LE, Dinh TA, Smith RA. An estrogen model: the relationship between body mass index, menopausal status, estrogen replacement therapy, and breast cancer risk. Comput Math Methods Med 2012; 2012: 792375.

  • 39.

    Chow LW, Lui KL, Chan JC, Chan TC, Ho PK, Lee WY, et al. Association between body mass index and risk of formation of breast cancer in Chinese women. Asian J Surg 2005; 28: 179-184.

  • 40.

    Rose DP, Vona-Davis L. Interaction between menopausal status and obesity in affecting breast cancer risk. Maturitas 2010; 66: 33-38.

  • 41.

    La Vecchia C, Giordano SH, Hortobagyi GN, Chabner B. Overweight, obesity, diabetes, and risk of breast cancer: interlocking pieces of the puzzle. Oncologist 2011; 16: 726-729.

  • 42.

    Adebamowo CA, Ogundiran TO, Adenipekun AA, Oyesegun RA, Campbell OB, Akang EE, et al. Waist-hip ratio and breast cancer risk in urbanized Nigerian women. Breast Cancer Res 2003; 5: R18-24.

  • 43.

    Gaudet MM, Carter BD, Patel AV, Teras LR, Jacobs EJ, Gapstur SM. Waist circumference, body mass index, and postmenopausal breast cancer incidence in the Cancer Prevention Study-II Nutrition Cohort. Cancer Causes Control 2014; 25: 737-745.

  • 44.

    Connolly BS, Barnett C, Vogt KN, Li T, Stone J, Boyd NF. A meta-analysis of published literature on waist-to-hip ratio and risk of breast cancer. Nutr Cancer 2002; 44: 127-138.

  • 45.

    Harvie M, Hooper L, Howell AH. Central obesity and breast cancer risk: a systematic review. Obes Rev 2003; 4: 157-173.

  • 46.

    Harris HR, Willett WC, Terry KL, Michels KB. Body fat distribution and risk of premenopausal breast cancer in the Nurses' Health Study II. J Natl Cancer Inst 2011; 103: 273-278.

  • 47.

    Lahmann PH, Hoffmann K, Allen N, van Gils CH, Khaw KT, Tehard B, et al. Body size and breast cancer risk: findings from the European prospective investigation into cancer and nutrition (EPIC). Int J Cancer 2004; 111: 762-771.

  • 48.

    Morimoto LM, White E, Chen Z, Chlebowski RT, Hays J, Kuller L, et al. Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States). Cancer Causes Control 2002; 13: 741-751.

  • 49.

    Lahmann PH, Lissner L, Gullberg B, Olsson H, Berglund G. A prospective study of adiposity and postmenopausal breast cancer risk: the Malmo Diet and Cancer Study. Int J Cancer 2003; 103: 246-252.

  • 50.

    Baer HJ, Colditz GA, Rosner B, Michels KB, Rich-Edwards JW, Hunter DJ, Willett WC. Body fatness during childhood and adolescence and incidence of breast cancer in premenopausal women: a prospective cohort study. Breast Cancer Res 2005; 7: R314-325.

  • 51.

    Baer HJ, Tworoger SS, Hankinson SE, Willett WC. Body fatness at young ages and risk of breast cancer throughout life. Am J Epidemiol 2010; 171: 1183-1194. ##.