Relationship between idiopathic hypercalciuria and urinary tract infection in children of 1-14 years of age

authors:

avatar Mohamad Sadegh Yazdiha , avatar Javad Behshad , avatar Seyyed Mohamad Hoseini , avatar Mohammadreza Razavi , * , avatar Alireza Emadi , avatar Raheb Ghorbani ORCID


how to cite: Yazdiha M S, Behshad J, Hoseini S M, Razavi M, Emadi A, et al. Relationship between idiopathic hypercalciuria and urinary tract infection in children of 1-14 years of age. koomesh. 2016;18(1):e151156. 

Abstract

Introduction: Urinary  tract  infection (UTI) is  one  of the  most  common  causes of  chronic  renal  failure  of  children. Therefore  diagnosis  of  predisposing  factors  have  an  important  role to  prevent  renal  damage. This Study was performed to investigate the association between idiopathic hypercalciuria and urinary tract infection in children 1-14 years of age admitted to Amiralmomenin hospital of Semnan (Iran). Materials and Methods: This was a case-control study in which 75 children with   UTI (without renal stone  and  urinary  tract  malformation) and  a control  group  of  75  children without UTI were  investigated. We measured random urine calcium to creatinine ratio in these children. In order to ruled out of secondary hypercalciuria, serum calcium, phosphor alkalene phosphatase, venous blood gases also were measured. Results: 67 out of 150 patients (89.3%) were females and the rest were males. The mean (± SD) age of children with UTI were 3.83 ± 2.78 years and in control group were 3.88 ± 2.88  years which the difference was not significant (p = 0.907). Idiopathic hypercalciuria in 40% (n = 30) of children with UTI and 13.3% (n = 10) of children without UTI was found (P

References

  • 1.

    Fesharakinia A, Taheri F, Saadatjoo SA. The prevalence of urinary tract infection in 7-years children of Birjand city: Screening of urinary tract infection in the children before attendance to primary school? Pathobiology 2006; 9: 53-56.

  • 2.

    Kleigman R, Behrman R, Jenson H. Nelson textbook of pediatrics. hilladelphia: Saunders Elsevier; 2012; 327451096-2.

  • 3.

    Jahanshahifard S, Askari F. Comparative Study of factors related to urinary tract infection in children. Urmia Med J 2010; 21: 37-41.(Persian).

  • 4.

    Nobahar M. Factors affecting the safety of hemodialysis' patients in dialysis ward and their strengthening strategies. Koomesh 2016; 17: 547-562. (Persian).

  • 5.

    Delphan M, Rashid Lamir A, editors. The effects of two weight loss protocol onresting plasma concentration of IL-6 inoverweight and obese health sedentaryfemale of college students. 22nd International Congress on Pediatrics, Tehran; 2010.

  • 6.

    Dalirani R, Mahyar A, Moshiri A, Ayazi P, Yavari S, Golnavaz S. Hypercalciuria in urinary tract infection of children in Qods teaching hospital of Qazvin. J Qazvin Univ Med Sci 2011; 15. (Persian).

  • 7.

    Rahimi M, tajbakhsh m, Razaghi M, Tajeddin E, Alebouyeh M, Rajabi Bazl M, Zali MR. Frequency of -lactamase producing isolates of Escherichia coli and their diversity in enzyme activities among the resistance isolates from patients with diarrhea and nosocomial infections in Tehran, Iran. Koomesh 2014; 15: 197-205.

  • 8.

    Stojanovi VD, Miloevi BO, Djapi MB, Bubalo JD. Idiopathic hypercalciuria associated with urinary tract infection in children. Pediatr Nephrol 2007; 22: 1291-1295.

  • 9.

    Sadeghi-Bojd S, Hashemi M. Hypercalciuria and recurrent urinary tract infections among children in Zahedan, Iran. J Pak Med Assoc 2008; 58: 624-626.

  • 10.

    Nacaroglu HT, Demircin G, Blbl M, Erdogan , Akyz SG, altik A. The association between urinary tract infection and idiopathic hypercalciuria in children. Renal Failure 2013; 35: 327-332.

  • 11.

    Langman C, Moore E. Hypercalciuria in Clinical Pediatrics A Review. Clin Pediatr 1984; 23: 135-137.

  • 12.

    Penido MG, Diniz JS, Moreira ML, Tupinamba AL, Franca A, Andrade BH, Souto MF. Idiopathic hypercalciuria: presentation of 471 cases. J Pediatr 2001; 77: 101-104.

  • 13.

    Weisinger JR, Alonzo E, Carlini RG, Paz-Martinez V, Martinis R, Bellorin-Font E. Bone disease in hypercalciuria: a new form of osteodystrophy? Nephrol Dial Transplant 1998; 13: 88-90.

  • 14.

    Ghassemi K, Esteghamati M, Rahmati MB, Hamedi Y, Nazemi A, Molavi MA, Alavi SA. Relation of Symptomatic Idiopathic Hypercalciuria with Urinary Tract Infection in Patients Attending to Children Hospital. Asian J Med Pharm Res 2013; 3: 102-104.

  • 15.

    Lopez M, Castillo LA, Chvez JB, Ramones C. Hypercalciuria and recurrent urinary tract infection in Venezuelan children. Pediatr Nephrol 1999; 13: 433-437.

  • 16.

    Nikibakhsh A, Mahmoudzadeh H, Karamyar M, Ghafari A, Yekta Z, Vafaei M. Hypercalciuria associated with recurrent urinary tract infections in children. J Tabriz Uni Med Sci 2007; 29: 121-124. (Persian).

  • 17.

    Biyikli NK, Alpay H, Guran T. Hypercalciuria and recurrent urinary tract infections: incidence and symptoms in children over 5 years of age. Pediatr Nephrol 2005; 20: 1435-1438.

  • 18.

    Gheissari A, Adjoodani T, Eshraghi P. Hypercalciuria, a promoting factor to urinary tract infection in children. Urology Annal 2009; 1: 52. (Persian).

  • 19.

    Abdullah M, Hossain MS, Khan MA, Uddin MN, Ishrat R, Jahan NWB, et al. Hypercalciuria is an important cause of urinary tract infection in children. Bangladesh Med J 2014; 43: 9-12##.