Comparison of the total antioxidant capacity of serum and saliva in the type-I diabetic patients

authors:

avatar AliAkbar MalekiRad , avatar Ali Fani , * , avatar MohammadAli ShariatZadeh , avatar Akram Ranjbar

Koomesh: Vol.7, issue 1; 89-94
published online: February 15, 2006
article type: Research Article

how to cite: MalekiRad A, Fani A, ShariatZadeh M, Ranjbar A. Comparison of the total antioxidant capacity of serum and saliva in the type-I diabetic patients. koomesh. 2006;7(1):e152090. 

Abstract

Introduction: Diabetes is one of the most important common chronic illness which is increasing in the world as an example in Iran. This illness is the fourth factor of death in the most of the developed countries. On the other hand, weakening of the antioxidant defensive system may lead to different diseases such as diabetes which in this study the capacity of antioxidant serum and saliva in diabetics patients of type I in the comparison with the control group is investigated in order to study the diagnostic value. Material and Methods: This is a cross - sectional study in which those under studying are 42 people of type I of diabetics called on to Arak diabetes center as the appointed group compared with 42 people as the control group which were in the same age and sex and other criterions of entrance with the first group. The total antioxidant capacity in serum and saliva of these people were measured by FRAP method. Results: The mean and standard deviation (mean SD) of the total antioxidant capacity of serum and saliva in the case group were in this manner: 2.51 .088, 1.73 .072 and in the control group were: 2.9 .107, 1.97 .090. Conclusion: From the statistical viewpoint the decrease in the total antioxidant capacity of serum in the case group was meaningful, but the decrease in the total antioxidant capacity of saliva was not meaningful. In other words the production of free radicals in case group which can be probably the case of disease has been increased and therefore the antioxidant defensive system has been weakened. It is advised to these people to consume more natural antioxidant in order to decrease the damages caused by free radicals.