Abstract
Introduction: Vaspin (visceral adipose tissue-derived serine protease inhibitor) has been recently identified as a novel adipocytokine with insulin-sensitizing effects. There is a limited information available regarding the effect of exercise training on serum vaspin concentration. The purpose of this study was to investigate the effect of resistance training on serum vaspin levels and some inflammatory markers. Material and Methods: Sixteen male Wister rats (288 ± 19g) were randomly divided into experimental and control groups. The experimental group was subjected to a resistance training program with the use of a ladder (3 days/wk, for 4 wk). Body weight and fasting serum levels of glucose, insulin, vaspin, C-reactive protein (CRP), interleukin (IL)-6, and tumor necrosis factor (TNF)-α were measured. Results: following four weeks resistance training, serum vaspin level was significantly lower in the experimental group than the control group (P< 0.05). The resistance training significantly decreased serum levels of IL-6, CRP and TNF-α in the experimental group as compared to the control group (P< 0.05). Conclusion: This study indicated that resistance training could decrease serum vaspin levels as well as inflammatory markers concentrations. Decreased of serum vaspin levels may be an adjustment mechanism in response to insulin sensitizing improvement and decline of inflammatory markers levels in trained rats.
Keywords
Resistance training, Insulin resistance, Rats مقاومت تمرینی، سرپینها، مقاومت به انسولین، موشهای صحرایی
Copyright
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.