Effect of peppermint extract on food intake and body weight following immobilization stress in mice

Reza Rahmati; Shariar Semnani; Hamid Sepehri; Gholamreza Vaghari; SeyyedMehran Hoseini; Zahra HajiMashhadi; Rasool Mohammadi

Koomesh

Journal of Semnan University of Medical Sciences

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Effect of peppermint extract on food intake and body weight following immobilization stress in mice

Author(s):

Reza Rahmati^,*,

Shariar Semnani^,**,

Hamid Sepehri^,***,

Gholamreza Vaghari^,****,

SeyyedMehran Hoseini^,*****,

Zahra HajiMashhadi^,******,

Rasool Mohammadi^,*******

Corresponding Authors:

Koomesh:Vol. 14, issue 3; 367-372

Published online:May 25, 2013

Article type:Research Article

Received:Mar 05, 2012

Accepted:Apr 08, 2013

How to Cite:Reza RahmatiShariar SemnaniHamid SepehriGholamreza VaghariSeyyedMehran HoseiniZahra HajiMashhadiRasool Mohammadiet al.Effect of peppermint extract on food intake and body weight following immobilization stress in mice.koomesh.14(3):e152589.

Abstract

Introduction: Stress interferes with the different physiological performance systems and causing in some behavioral responses that including food intake. Considering the effects of peppermint in traditional medicine as an effective drug on some disorders in this study its effect on food intake and body weight following immobilization stress were studied. Materials and Methods:: Male mice were divided randomly into the three groups the first group as a control group, second group as a stress group and third group as stress plus peppermint oil group with ten mice in each. The second group as a stress group received immobilization stress four hours for three days. Third group as stress plus peppermint oil group received stress in addition to administration of 27 mg/kg peppermint oil intraperitoneally before stress. After three days of treatment, food intake and body weight were measured. Results: Based on food intake, there were statistical differences between control and stress groups (P=0.001), stress and stress plus peppermint oil (P=0.001), control and stress plus peppermint oil (P=0.025). Based on body weight, there were statistical differences in stress and stress+ peppermint oil groups before and after experiment (P

Keywords

Peppermint oil, Mice, Immobilization stress, food intake, body weight

عصاره نعناع، موش سوری، استرس بی‌حرکتی، میزان دریافت غذا، وزن

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