Diagnosis of epilepsy and evaluation of anti-epileptic drugs by resting qEEG analysis in the man and women patients

Asieh Mohammadi; Majid Hassanpourezatti; Hamid Reza Navidi; korosh GhareGhezli; saied Barjesteh

Koomesh

Journal of Semnan University of Medical Sciences

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Diagnosis of epilepsy and evaluation of anti-epileptic drugs by resting qEEG analysis in the man and women patients

Author(s):

Asieh Mohammadi,

Majid Hassanpourezatti

^,*,

Hamid Reza Navidi,

korosh GhareGhezli,

saied Barjesteh

Koomesh:Vol. 15, issue 2; 146-153

Published online:Feb 28, 2013

Article type:Research Article

Received:Dec 01, 2012

Accepted:Sep 01, 2013

How to Cite:Asieh MohammadiMajid HassanpourezattiHamid Reza Navidikorosh GhareGhezlisaied BarjestehDiagnosis of epilepsy and evaluation of anti-epileptic drugs by resting qEEG analysis in the man and women patients.koomesh.15(2):e152627.

Abstract

Introduction: Currently, the recording and digitalization of EEG is possible due to development of electrophysiological instruments. Increased in repeated patterns in EEG as a time series indicates occurrence of neuronal hyper-synchronization and epilepsy. The occurrence of this phenomenon can be evaluated by self-similarity exponents. In this research, epilepsy was detected and efficacy of its medication by attention the patient sex was studied with help of these exponents. Materials and Methods: Self-similarity exponents α1, α2 and η and ν factors were calculated by detrended fluctuation analysis method for two minute resting EEG recording from 16 healthy persons (8 men and 8 women) and 21 generalized epileptic patients (8 men and 13 women) that received different anti-seizure medications. Body mass index and waist to hip ratio of all participation was measured. Results: The metabolic indexes have not any significant difference between groups. Only self similarity exponent α2 was shown significant (p

Keywords

Epilepsy, Electroencephalography, Anticonvulsants, Fractals, Sex Characteristics

صرع، ثبت تغییرات الکتریکی مغز، ضد تشنج ها، فراکتال ها، ویژگی‌های جنسی

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