Koomesh
Journal of Semnan University of Medical Sciences
Outlines
Anti-inflammatory and anti-oxidative effects of Ganoderma lucidum on liver injury induced by doxorubicin in rats
Author(s):
Published online:Jul 02, 2023
Article type:Research Article
Received:Jul 02, 2022
Accepted:Jul 02, 2023
How to Cite:Reza Hemmatan AtarbashiAmir RezaKaramibonariTarlan FarahvashAnti-inflammatory and anti-oxidative effects of Ganoderma lucidum on liver injury induced by doxorubicin in rats.koomesh.25(3):e152827.
Abstract
References
- 1.Andrejc DC, Knez Z, Marevci MK. Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front Pharmacol 2022; 2757.
- 2.Gao JJ, Min BS, Ahn EM, Nakamura N, Lee HK, Hattori M. New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. Chemic Pharmac Bulletin 2002; 50: 837-840.
- 3.Hu Z, Du R, Xiu L, Bian Z, Ma C, Sato N, et al. Protective effect of triterpenes of Ganoderma lucidum on lipopolysaccharide-induced inflammatory responses and acute liver injury. Cytokine 2020; 127: 154917.
- 4.Liu GQ, Zhang KC. Mechanisms of the anticancer action of Ganoderma lucidum (Leyss. ex Fr.) Karst. a new understanding. Integrative Plant Bio 2005; 47: 129-135.##https://doi.org/10.1111/j.1744-7909.2005.00037.x.
- 5.Wang YY, Khoo KH, Chen ST, Lin CC, Wong CH, Lin CH. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorganic Med Chem 2002; 10: 1057-1062.
- 6.El-Mekkawy S, Meselhy MR, Nakamura N, Tezuka Y, Hattori M, Kakiuchi N, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochem 1998; 49: 1651-1657.
- 7.Fang QH, Tang YJ, Zhong JJ. Significance of inoculation density control in production of polysaccharide and ganoderic acid by submerged culture of Ganoderma lucidum. Process Biochem 2002; 37: 1375-1379.
- 8.Su CY, Shiao MS, Wang CT. Potentiation of ganodermic acid S on prostaglandin E1-induced cyclic AMP elevation in human platelets. Thrombosis Res 2000; 99: 135-145.
- 9.Saltarelli R, Ceccaroli P, Iotti M, Zambonelli A, Buffalini M, Casadei L, et al. Biochemical characterisation and antioxidant activity of mycelium of Ganoderma lucidum from Central Italy. Food Chem 2009; 116: 143-151.##https://doi.org/10.1016/j.foodchem.2009.02.023.
- 10.Lin WC, Lin WL. Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats. Gastroenterology 2006; 12: 265.
- 11.Park EJ, Ko G, Kim J, Sohn DH. Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction. Biol Pharm Bull 1997; 20: 417-420.
- 12.Ahmed OM, Galaly SR, Raslan M, Mostafa MA. Thyme oil and thymol abrogate doxorubicin-induced nephrotoxicity and cardiotoxicity in Wistar rats via repression of oxidative stress and enhancement of antioxidant defense mechanisms. Biocell 2020; 44: 41.##https://doi.org/10.32604/biocell.2020.08157.
- 13.Shamsi F. Nanotechnology application in cancer treatment. Koomesh 2019; 21: 579-589. (Persian).
- 14.Shahani S, Sahranavard M, Amiri F, Abedi M, Noaparast Z. Beneficial effects of Pimpinella anisum L. ethanol and aqueous extracts on L-asparaginase-associated hepatotoxicity using specific 99mTc-Phytate biodistribution studies in rats. Koomesh 2022; 24: 554-565. (Persian).
- 15.El-Moselhy MA, El-Sheikh AA. Protective mechanisms of atorvastatin against doxorubicin-induced hepato-renal toxicity. Biomed Pharmacother 2014; 68: 101-110.
- 16.Altnkaynak Y, Kural B, Akcan BA, Bodur A, zer S, Yulu E, et al. Protective effects of L-theanine against doxorubicin-induced nephrotoxicity in rats. Biomed Pharmacother 2018; 108: 1524-1534.
- 17.Yagmurca M, Erdogan H, Iraz M, Songur A, Ucar M, Fadillioglu E. Caffeic acid phenethyl ester as a protective agent against doxorubicin nephrotoxicity in rats. Clin Chim Acta 2004; 348: 27-34.
- 18.Kuzu M, Yldrm S, Kandemir FM, Kkler S, alayan C, Trk E, et al. Protective effect of morin on doxorubicin-induced hepatorenal toxicity in rats. Chem Biol Interact 2019; 308: 89-100.
- 19.Hadi N, Yousif NG, Al-Amran FG, Huntei NK, Mohammad BI, Ali SJ. Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response. BMC Cardiovas Dis 2012; 12: 1-7.
- 20.Fathima AT, Reenaa M. Anticancer and antibacterial activity of ganoderma lucidum. Int J Curr Microbiol App Sci 2016; 5: 891-909.##https://doi.org/10.20546/ijcmas.2016.510.097.
- 21.Hassan HM, Al-Wahaibi LH, Elmorsy MA, Mahran YF. Suppression of cisplatin-induced hepatic injury in rats through alarmin high-mobility group box-1 pathway by Ganoderma lucidum: theoretical and experimental study. Drug Des Dev Ther 2020; 14: 2335.
- 22.Uchiyama M, Mihara M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978; 86: 271-278.
- 23.Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121-126.
- 24.Peinnequin A, Mouret C, Birot O, Alonso A, Mathieu J, Clarenon D, et al. Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green. BMC Immunol 2004; 5: 1-0.
- 25.Rolo AP, Teodoro JS, Palmeira CM. Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. Biol Med 2012; 52: 59-69.
- 26.Al-Oanzi ZH, Elasbali AM, Alruwaili NK, Alotaibi NH, Alharbi KS, Alzarea AI, et al. Protective effect of baicalein alone and losartan-baicalein combination therapy on doxorubicin-induced hepatotoxicity in rats. Toxicol Environ Health Sci 2020; 12: 45-54.##https://doi.org/10.1007/s13530-020-00037-7.
- 27.Shaker RA, Abboud SH, Assad HC, Hadi N. Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis. BMC Pharmacother Toxicol 2018; 19: 3.
- 28.Saltarelli R, Ceccaroli P, Iotti M, Zambonelli A, Buffalini M, Casadei L, et al. Biochemical characterisation and antioxidant activity of mycelium of Ganoderma lucidum from Central Italy. Food Chem 2009; 116: 143-151.##https://doi.org/10.1016/j.foodchem.2009.02.023.
- 29.Fernandez ML, West KL. Mechanisms by which dietary fatty acids modulate plasma lipids. J Nutr 2005; 135: 2075-2078.
- 30.Lin LJ, Shiao MS, Yeh SF. Seven new triterpenes from Ganoderma lucidum. J Nat Prod 1988; 51: 918-924.
- 31.Tulubas F, Gurel A, Oran M, Topcu B, Caglar V, Uygur E. The protective effects of -3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats. Toxicol Ind Health 2015; 31: 638-644.
- 32.Hirotani M, Ino C, Furuya T, Shiro M. Ganoderic acids T, S and R. New triterpenoids from the cultured mycelia of Ganoderma lucidum. Chem Pharm Bull 1986; 34: 2282-2285.##https://doi.org/10.1248/cpb.34.2282.
- 33.Hossen M, Billah Prince M, Tanvir EM, Chowdhury M, Rahman M, Alam F, et al. Ganoderma lucidum and Auricularia polytricha mushrooms protect against Carbofuran-induced toxicity in rats. Evi Based Complement Alternat Med 2018; 2018.
- 34.Susilo RJ, Winarni D, Husen SA, Hayaza S, Punnapayak H, Wahyuningsih SP, et al. Hepatoprotective effect of crude polysaccharides extracted from Ganoderma lucidum against carbon tetrachloride-induced liver injury in mice. Vet World 2019; 12: 1987.
Copyright
© 2023, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
comments
Leave a comment here
Comments
Number of Comments:0Purchasing Reprints
- Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.
Search Relations
Author(s):
Related Articles