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The effect of oral administration Lactococcus lactis probiotic vaccine carrying Brucella abortus BLS antigen on changes in blood leukocyte ratio and CRP as biomarkers in brucellosis

Author(s):
Fatehi FatehiFatehi Fatehi, Abbas DoostiAbbas DoostiAbbas Doosti ORCID,*, Mohammad Saeid JamiMohammad Saeid Jami

Koomesh:Vol. 25, issue 6; 640-646
Published online:Dec 01, 2023
Article type:Research Article
Received:Jun 01, 2023
Accepted:Jan 01, 2023
How to Cite:Fatehi FatehiAbbas DoostiMohammad Saeid JamiThe effect of oral administration Lactococcus lactis probiotic vaccine carrying Brucella abortus BLS antigen on changes in blood leukocyte ratio and CRP as biomarkers in brucellosis.koomesh.25(6):e152862.

Abstract

References

  • 1.
    Sing A, editor. Zoonoses-Infections affecting humans and animals: Focus on public health aspects. Springer; 2014 Dec 8.##https://doi.org/10.1007/978-94-017-9457-2.
  • 2.
    Amjadi O, Rafiei A, Mardani M, Zafari P, Zarifian A. A review of the immunopathogenesis of Brucellosis. Infect Dis 2019; 51: 321-333.
  • 3.
    Kurmanov B, Zincke D, Su W, Hadfield TL, Aikimbayev A, Karibayev T, et al. Assays for identification and differentiation of Brucella species: A review. Microorganisms 2022; 10: 1584.
  • 4.
    Burn GL, Foti A, Marsman G, Patel DF, Zychlinsky A. The neutrophil. Immunity 2021; 54: 1377-1391.
  • 5.
    Rezaei M, Rabbani-Khorasgani M, Zarkesh-Esfahani SH, Emamzadeh R, Abtahi H. Prediction of the Omp16 Epitopes for the development of an Epitope-based vaccine against Brucellosis. Infect Disord Drug Targets 2019; 19: 36-45.
  • 6.
    Ribeiro LA, Azevedo V, Le Loir Y, Oliveira SC, Dieye Y, Piard JC, Gruss A, Langella P. Production and targeting of the Brucella abortus antigen L7/L12 in Lactococcus lactis: a first step towards food-grade live vaccines against brucellosis. Appl Environ Microbiol 2002; 68: 910-916.
  • 7.
    Badmasti F, Habibi M, Firoozeh F, Fereshteh S, Bolourchi N, Goodarzi NN. The combination of CipA and PBP-7/8 proteins contribute to the survival of C57BL/6 mice from sepsis of Acinetobacter baumannii. Microb Pathog 2021; 158: 105063.
  • 8.
    Liu X, Qi L, Lv J, Zhang Z, Zhou P, Ma Z, et al. The immune response to a recombinant Lactococcus lactis oral vaccine against foot-and-mouth disease virus in mice. Biotechnol Lett 2020; 42: 1907-1917.
  • 9.
    Bermdez-Humarn LG, Langella P, Cortes-Perez NG, Gruss A, Tamez-Guerra RS, Oliveira SC, et al. Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production. Infect Immun 2003; 71: 1887-1896.
  • 10.
    O'callaghan D. Human brucellosis: recent advances and future challenges. Infect Dis Poverty 2020; 9: 1-2.
  • 11.
    Blasco JM. Control and eradication strategies for Brucella melitensis infection in sheep and goats. Prilozi 2010; 31: 145-165.
  • 12.
    Dorneles E, Sriranganathan N, Lage AP. Recent advances in Brucella abortus vaccines. Vet Res 2015; 46: 76.
  • 13.
    Vishnu US, Sankarasubramanian J, Gunasekaran P, Rajendhran J. Novel vaccine candidates against Brucella melitensis identified through reverse vaccinology approach. Omics 2015; 19: 722-729.
  • 14.
    D'Souza R, Pandeya DR, Hong ST. Lactococcus lactis: an efficient Gram positive cell factory for the production and secretion of recombinant protein. Biomed Res 2012; 23: 1-7.
  • 15.
    Rezaei M, Rabbani-Khorasgani M, Zarkesh-Esfahani SH, Emamzadeh R, Abtahi H. Lactococcus-based vaccine against brucellosis: IgG immune response in mice with rOmp16-IL2 fusion protein. Arch Microbiol 2021; 203: 2591-2596.
  • 16.
    Akbari R, Sekhavati MH, Bahrami A, Majidzadeh Heravi R, Yousefi S. Production of brucella lumazine synthase recombinant protein to design a subunit vaccine against undulant fever. Arch Razi Inst 2019; 74: 1-6.
  • 17.
    Tirbakhsh Gouran S, Doosti A, Jami MS. Expression of brucella abortus Omp25 protein in lactococcus lactis probiotic bacteria. J Mazandaran Univ Med Sci 2023; 32: 16-31.
  • 18.
    Moreno E, Barquero-Calvo E. The role of neutrophils in brucellosis. Microbiol Mol Biol Rev 2020; 84: e00048-20.
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