Assessing anthropometric indices changes and related factors in patients under methadone maintenance therapy

authors:

avatar Afshin Hemmati , avatar Seyedeh Fatemeh Yaghoobi , avatar Hossein Hatami , avatar Mahdi Shadnoush ORCID , * , avatar Mansoureh Baniasadi

Koomesh: Vol.20, issue 3; 447-452
published online: September 05, 2018
article type: Research Article
received: June 03, 2017
accepted: September 05, 2017

How To Cite Hemmati A, Yaghoobi S F, Hatami H, Shadnoush M, Baniasadi M. Assessing anthropometric indices changes and related factors in patients under methadone maintenance therapy. koomesh. 2018;20(3):e152977. 

Abstract

Introduction: Methadone treatment is one of the treatments for addiction. Methadone is an opioid agonist which chronic exposure to it leads to side effects such as weight gain. Hence, recognizing the different dimensions of abuse treatment and its consequences can be effective in improving the treatment process, better control of the patient;#39s condition and preventing subsequent problems. The aim of this study was to investigate factors related to weight variation and anthropometry in patients undergoing methadone maintenance therapy. Materials and Methods: In this study, 150 patients referred to the Semnan Substance Abuse Treatment Center (from 2011.3.21 to 2014.11.30). In this study, changes in weight and body mass index in patients and its relationship with variables such as age, smoking, education level, drug use time, marital status and employment were investigated. Results: The results of this study indicate a significant difference in weight and body mass index in the first 3 months compared to the 3rd month in subjects with methadone maintenance treatment, which is more than the first three months (p

References

  • 1.

    Goodman A. Addiction: definition and implications. Br J Addict 1990; 85: 1403-1408.

  • 2.

    Xiao L, Wu Z, Luo W, Wei X. Quality of life of outpatients in methadone maintenance treatment clinics. J Acquir Immune Defic Syndr 2010; 53: S116-120.

  • 3.

    Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S, Murray CJ. Selected major risk factors and global and regional burden of disease. The Lancet 2002; 360: 1347-1360.

  • 4.

    Hall WD, Mattick RP. Oral substitution treatments for opioid dependence. The Lancet 2008; 371: 2150-2151.

  • 5.

    Shinebourne P, Smith JA. Alcohol and the self: An interpretative phenomenological analysis of the experience of addiction and its impact on the sense of self and identity. Add Res Theor 2009; 17: 152-167.

  • 6.

    Rostami R, Sardar Pour Goodarzi S, Bolhari J. Ultra Rapid Detoxification: A Review of advantages and Disadvantages. Iran J Psychiatry Clin Psychol 2003; 8: 16-31. (Persian).

  • 7.

    Stotts AL, Dodrill CL, Kosten TR. Opioid dependence treatment: options in pharmacotherapy. Expert Opin Pharmacother 2009; 10: 1727-1740.

  • 8.

    Kaye AD, Gevirtz C, Bosscher HA, Duke JB, Frost EA, Richards TA, Fields AM. Ultrarapid opiate detoxification: a review. Can J Anaesth 2003; 50: 663-671.

  • 9.

    Singh J, Basu D. Ultra-rapid opioid detoxification: current status and controversies. J Postgrad Med 2004; 50: 227-232.

  • 10.

    Loimer N, Schmid R, Presslich O, Lenz K. Naloxone treatment for opiate withdrawal syndrome. Br J Psychiatry 1988; 153: 851-852.

  • 11.

    Ward J, Matlick R, Hall W. Methadone maintenance treatment and other opioid replacement therapies Amsterdam. J Harwood Acad 1998; 23: 571.

  • 12.

    Erdelyan M YC. Methadone maintenance treatment: A community planning guide. Centre for Addiction and Mental Health 2009; Available: http://knowledgex.camh.net/policy_health/substance_use/mmt_community_guide/Documents/mmt_community_guide.

  • 13.

    Mysels DJ, Vosburg S, Benga I, Levin FR, Sullivan MA. Course of weight change during naltrexone vs. methadone maintenance for opioid-dependent patients. J Opioid Manag 2011; 7: 47-53.

  • 14.

    Atkinson R, editor. Opioid regulation of food intake and body weight in humans. Federation proceedings; 1987.

  • 15.

    Mohs ME, Watson RR, Leonard-Green T. Nutritional effects of marijuana, heroin, cocaine, and nicotine. J Am Diet Assoc 1990; 90: 1261-1267.

  • 16.

    Nolan LJ, Scagnelli LM. Preference for sweet foods and higher body mass index in patients being treated in long-term methadone maintenance. Subst Use Misuse 2007; 42: 1555-1566.

  • 17.

    Rajs J, Pettersson A, Thiblin I, Olsson-Mortlock C, Fredriksson A, Eksborg S. Nutritional status of deceased illicit drug addicts in Stockholm, Sweden-A longitudinal medicolegal study. J Forensic Sci 2004; 49: 320-329.

  • 18.

    Imes CC, Burke LE. The obesity epidemic: the United States as a cautionary tale for the rest of the world. Curr Epidemiol Rep 2014; 1: 82-88.

  • 19.

    Papas MA, Trabulsi JC, Axe M, Rimmer JH. Predictors of obesity in a US sample of high school adolescents with and without disabilities. J Sch Health 2016; 86: 803-812.

  • 20.

    Sarshar N, Khajavi A. The prevalence of obesity in females of 15-65 years of age in Gonabad, Iran. Horizon Med Sci 2006; 12: 38-43.

  • 21.

    Asgary S, Sarrafzadegan N, Naderi GA, Rozbehani R. Effect of opium addiction on new and traditional cardiovascular risk factors: do duration of addiction and route of administration matter? Lipids Health Dis 2008; 7: 42.

  • 22.

    Field AE, Coakley EH, Must A, Spadano JL, Laird N, Dietz WH, Rimm E, Colditz GA. Impact of overweight on the risk of developing common chronic diseases during a 10-year period. Arch Int Med 2001; 161: 1581-1586.

  • 23.

    Getz GS, Reardon CA. Nutrition and cardiovascular disease. Arterioscler Thromb Vasc Biol 2007; 27: 2499-2506.

  • 24.

    Parvaresh N, Sabahi AR, Mazhari S, Gilani H. A study of the sexual function, sleep, and weight status of patients after 6 months of methadone maintenance treatment. Addict Health 2015; 7: 24-29. (Persian).

  • 25.

    Fenn JM, Laurent JS, Sigmon SC. Increases in body mass index following initiation of methadone treatment. J Subst Abuse Treat 2014; 51: 59-63.

  • 26.

    Okruhlica L, Slezakova S. Weight changes of patients in methadone maintenance treatment during four years period. Cas Lek Cesk 2012; 151: 389-391.

  • 27.

    Montazerifar F, Karajibani M, Lashkaripour K. Effect of methadone maintenance therapy on anthropometric indices in opioid dependent patients. Int J High Risk Behav Addict 2012; 1: 100-103.

  • 28.

    Okruhlica L, Slezkov S. [Weight gain among the patients in methadone maintenance program as come-back to population norm]. Cas Lek Cesk 2007; 147: 426-430.

  • 29.

    Erem C, Arslan C, Hacihasanoglu A, Deger O, Topba M, Ukinc K, Ersz H, Telatar M. Prevalence of obesity and associated risk factors in a Turkish population (Trabzon city, Turkey). Obes Res 2004; 12: 1117-1127.

  • 30.

    Wang Q. Smoking and body weight: evidence from China health and nutrition survey. BMC Public Health 2015; 15: 1238.

  • 31.

    Pomerleau J, McKeigue P, Chaturvedi N. Factors associated with obesity in South asian, afro-caribbean and European women. Int J Obes Relat Metab Disord 1999; 23: 25-33.

  • 32.

    Sasaki T. Age-Associated Weight Gain, Leptin, and SIRT1: A possible role for hypothalamic SIRT1 in the prevention of weight gain and aging through modulation of leptin sensitivity. Front Endocrinol (Lausanne) 2015; 6: 109.

  • 33.

    Williams PT, Wood PD. The effects of changing exercise levels on weight and age-related weight gain. Int J Obes 2006; 30: 543-551.

  • 34.

    Mahan LK, Escott-Stump S, Raymond JL. Krause's food & the nutrition care process: Elsevier Health Sciences; 2012.

  • 35.

    HajianTilaki K, Heidari B. Prevalence of obesity, central obesity and the associated factors in urban population aged 2070 years, in the north of Iran: a populationbased study and regression approach. Obes Rev 2007; 8: 3-10.

  • 36.

    Wilson SE. Marriage, gender and obesity in later life. Econ Hum Biol 2012; 10: 431-453.##.