Helicobacter pylori colonization in children with Adenotansillar hypertrophy

authors:

avatar Najmeh Dostmohammadian , * , avatar Navid Danaee , avatar Nooshin Rahimi , avatar Raheb Ghorbani ORCID

Koomesh: Vol.20, issue 4; 688-691
published online: March 03, 2018
article type: issue_documents_importer
received: January 09, 2018
accepted: February 03, 2018

how to cite: Dostmohammadian N, Danaee N, Rahimi N, Ghorbani R. Helicobacter pylori colonization in children with Adenotansillar hypertrophy. koomesh. 2018;20(4):e153012. 

Abstract

Introduction: Adenotonsillar hypertrophy is one of the most common causes of upper airway obstruction in children. Recent studies have shown colonization or not colonization of helicobacter pylori (HP) in adenotonsillar tissue. According to this, we decided to make a study in this field and investigate HP colonization in children with adenotansillar hypertrophy in semnan city. Materials and Methods: In this study, in ENT department of Amir al Moemenin Hospital in Semnan, Iran، 30 patient with adenotosillar hypertrophy, were surgeried adenotansilectomy, introduced in this study. For investigating colonization of HP, Rapid Ureas Test was done on 90 specimens (60 Tonsilar specimens and 30 Adenoid specimens). Results: Mean±SD of age of children was 8.9 ±2.6. Rapid Ureas Test in 14 (15.6%) specimens, 7/6% tonsil biopsy and 9/8% adenoid specimens were positive. Conclusion: In this study, we have found colonization of HP in adenotonsilar tissue.  However, more special tests are needed to provide a definitive judgment.  

References

  • 1.

    Goodwin CS, Worsley BW. Microbiology of helicobacter pylori. Gastroenterol Clin North Am 1993; 22: 5-19.

  • 2.

    Amieva MR, El-omar EM. Host-bacterial interactions in helicobacter pylori infection. Gastroenterology 2008; 134: 306-323.

  • 3.

    Pounder RE, Ng D. The prevalence of helicobacter pylori infection in different countries. Aliment Pharmacol Ther 1995; 9: 33-39.

  • 4.

    Abdel-Monem MH, Magdy EA, Nour YA, Harfoush RA, Ibreak A. Detection of helicobacter pylori in adenotonsillar tissue of children with chronic adenotonsillitis using rapid urease test, pcr and blood serology: a prospective study. Int J Pediatr Otorhinolaryngol 2011; 75: 568-572.

  • 5.

    Yarmohammadi ME, Jnmr Talebi H, Zayeri F. Colonization of helicobacter pylori in tonsil and adenoid. Daneshvar Med 2005; 12: 73-80. (Persian).

  • 6.

    Eyigor M, Eyigor H, Gultekin B, Aydin N. Detection of helicobacter pylori in adenotonsiller tissue specimens by rapid urease test and polymerase chain reaction. Eur Arch Otorhinolaryngol 2009; 266: 1611-1613.

  • 7.

    Vilarinho S, Guimaraes NM, Ferreira RM, Gomes B, Wen X, Vieira MJ, et al. Helicobacter pylori colonization of the adenotonsillar tissue: fact or fiction? Int J Pediatr Otorhinolaryngol 2010; 74: 807-811.

  • 8.

    Wibawa T, Surono A, Widodo I. Isolation of viable helicobacter pylori in the tonsillar tissues of chronic tonsillitis patients. J Infect Dev Ctries 2011; 5: 561-564.

  • 9.

    Gl O, Akal A, Sahin EM, Tekin K, Barutu O, Otkun MT, Dereky FS. Relationship between helicobacter pylori adenotonsillar colonization and frequency of adenotonsillitis in children. Balkan Med J 2013; 30: 301-304.

  • 10.

    Yilmaz MU, Kumcuoglu Z, Utkaner G, Yalniz O, Erkmen G. Computed tomography findings of tuberculous pleurisy. Int J Tuberc Lung Dis 1998; 2: 164-167.

  • 11.

    Pitkaranta A, Kolho KL, Rautelin H. Helicobacter pylori in children who are prone to upper respiratory tract infections. Arch Otolaryngol Head Neck Surg 2005; 131: 256-258.

  • 12.

    Bitar MA, Soweid A, Mahfouz R, Zaatari G, Fuleihan N. Is helicobacter pylori really present in the adenoids of children? Eur Arch Otorhinolaryngol 2005; 262: 987-992.

  • 13.

    Jelavic B, Bevanda M, Ostojic M, Leventic M, Vasilj M, Knezevic E. Tonsillar colonization is unlikely to play important role in helicobacter pylori infection in children. Int J Pediatr Otorhinolaryngol 2007; 71: 585-590.

  • 14.

    Vayisoglu Y, Ozcan C, Polat A, Delialioglu N, Gorur K. Does helicobacter pylori play a role in the development of chronic adenotonsillitis? Int J Pediatr Otorhinolaryngol 2008; 72: 1497-1501.

  • 15.

    Scadding G. Non-surgical treatment of adenoidal hypertrophy: the role of treating ige-mediated inflammation. Pediatr Allergy Immunol 2010; 21: 1095-1106.

  • 16.

    Minocha A, Raczkowski CA, Richards RJ. Is a history of tonsillectomy associated with a decreased risk of helicobacter pylori infection? J Clin Gastroenterol 1997; 25: 580-582.

  • 17.

    Aliakbari I, Safavi SA, Goljanian Tabrizi A, Bolfion M, Razaghi M, Goudarzi H, Dabiri H. The role of adenotonsillar tissues as a reservoir for helicobacter pylori and helicobacter hepaticus. Gastroenterol Hepatol Bed Bench 2011; 4: 153-158.

  • 18.

    Graham DY. Public health issues relating to Helicobacter pylori infection and global eradication.In:Graham DY, Genta RM, Dixon MF. Gastritis, Philadelphia, lippincott Williams and Wilkins, 1999; 241-247.

  • 19.

    Ochungo OP, Mugwe P, Masinde P, Waweru W. Prevalence of H. Pylori in Tonsillar Tissue of Patients with Chronic Recurrent Tonsillitis Using Rapid Urease Test in a Tertiary Referral Hospital in Sub Saharan Africa.Indian J Otolaryngol Head Neck Surg 2015;67:223-6.

  • 20.

    Kaymak M, Aydn M, Yazc S, Sar O, Erdem Gr O , Sayan M. Detection of Helicobacter pylori in adenoid tissue byreal-time polymerase chain reaction.Kulak Burun Bogaz Ihtis Derg 2014;24:78-82.

  • 21.

    Moghaddam Y, Rafeey M, Radfar R. Comparative assessment of Helicobacter py-lori colonization in children tonsillar tissues. Int J Pediatr Otorhinolaryngol 2009;73:1199-201.

  • 22.

    Siupsinskiene N, Katutiene I, Jonikiene V, Janciauskas D, Vaitkus S. Helicobacter pylori in the tonsillar tissue: a possible association with chronic tonsillitis and laryngopharyngeal reflux. J Laryngol Otol. 2017 ;131:549-556..##.

  • 23.

    Graham DY.Public health issues relating to Helicobacter pylori infection and global eradication.In:Graham DY,Genta RM,Dixon MF.Gastritis,Philadelphia,lippincott Williams and Wilkins 1999; 241-247.