A comparative study on the effects of fluoxetine  and tamoxifen on the treatment of mastalgia: A randomized clinical trial

Masoumeh Taghizadeh; Ismail Elahabadi; Zahra Kamiab; Mohammad Reza  Mohammadi Hassan; Maryam Mortazavi Lahijani; reza vazirinejad; Amir Moghadam-Ahmadi

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A comparative study on the effects of fluoxetine and tamoxifen on the treatment of mastalgia: A randomized clinical trial

Author(s):

Masoumeh Taghizadeh,

Ismail Elahabadi,

Zahra Kamiab

,

Mohammad Reza Mohammadi Hassan,

Maryam Mortazavi Lahijani,

reza vazirinejad,

Amir Moghadam-Ahmadi

^,*

Koomesh:Vol. 22, issue 4; 574-580

Published online:Dec 01, 2020

Article type:Research Article

Received:Jul 02, 2019

Accepted:May 01, 2020

How to Cite:Masoumeh TaghizadehIsmail ElahabadiZahra KamiabMohammad Reza Mohammadi HassanMaryam Mortazavi Lahijanireza vazirinejadAmir Moghadam-Ahmadiet al.A comparative study on the effects of fluoxetine and tamoxifen on the treatment of mastalgia: A randomized clinical trial.koomesh.22(4):e153216.

Abstract

Introduction: Mastalgia is a common complaint among women that requires proper medical treatment. The aim of this study was to investigate the comparison of fluoxetine versus tamoxifen effects on the mastalgia. Materials and Methods: In this clinical trial, 62 women, who referred to surgical clinic of Rafsanjan Ali-Ibn Abi-Talib hospital in 2017, with a complaint of breast pain were selected and treated with fluoxetine or tamoxifen. Correspondingly, informed consent, demographic checklists and the visual scale of the pain were completed in pre-treatment and then 4, 8 and 12 weeks after the treatment. Results: There was no significant difference between two groups in body mass index, duration of illness and duration of pain (P>0.05). Both fluoxetine and tamoxifen significantly reduced pain (P0.05). Conclusion: Both fluoxetine and tamoxifen were equally effective as alternative therapies against mastalgia

Keywords

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