A case report of heterogeneous blood transfusion in the operating room

authors:

avatar Sara Salarian , avatar Navid Shafigh , avatar Mohammad Sistanizad , avatar Fatemeh Talebi Kiasari , avatar Bahador Bagheri ORCID , *

Koomesh: Vol.23, issue 1; 180-182
published online: December 02, 2021
article type: Case Report
received: December 02, 2019
accepted: June 02, 2020

how to cite: Salarian S, Shafigh N, Sistanizad M, Talebi Kiasari F, Bagheri B. A case report of heterogeneous blood transfusion in the operating room. koomesh. 2021;23(1):e153254. 

Abstract

Introduction: Mismatched-blood transfusions in the ABO-system may lead to severe of complications such as intravascular hemolysis. Case report: A 49-year-old man suffering from a right lower limb injury due to accident was admitted to hospital. Vital signs were normal. X-ray showed a femoral neck fracture. Before surgery, all of lab tests were in normal values and B+ blood- group was reported. During surgery and due to blood loss, the patient underwent blood transfusion. At the end of transfusion, a mismatched blood bag was observed. The patient had received about 400 cc mismatched-blood. Transfusion was promptly terminated and the patient received extensive IV fluids in addition to a single dose of furosemide. The patient had stable status without signs of overt hemolysis. After 3 days stay at intensive care unit, he was transferred to the ward with a stable status. Conclusion: In spite of mismatched blood transfusion, the patient did not experience severe adverse events. To prevent this problem, different steps of blood transfusion should be checked by anesthesiologist

References

  • 1.

    Webster BH. Clinical presentation of haemolytic transfusion reactions. Anaesth Intensive Care 1980; 8: 115-119.

  • 2.

    Weinstock C, Mhle R, Dorn C, Weisel K, Hchsmann B, Schrezenmeier H, Kanz L. Successful use of eculizumab for treatment of an acute hemolytic reaction after ABOincompatible red blood cell transfusion. Transfusion 2015; 55: 605-610.

  • 3.

    Vamvakas EC, Blajchman MA. Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood 2009; 113: 3406-3417.

  • 4.

    Reverberi R, Reverberi L. Factors affecting the antigen-antibody reaction. Blood Transfus 2007; 5: 227.

  • 5.

    Ghasemi M, Malek B, Tavakolpour A, Vosoughian M, Dahi Taleghani M. Mismatched blood transfusion; case-report. Scientific J Iran Blood Transfus Organ 2013; 10. (Persian).

  • 6.

    Dahi M, Dabagh A. Transfusion of unmatched packed cells in a life threatening emergency case. Scientific J Iran Blood Transfus Organ 2006; 3. (Persian).

  • 7.

    Ti LK, Ang SBL, Chen FG. Survival after large ABO-incompatible blood transfusion. Can J Anesth 1998; 45: 916.##.