Comparison of influential factors affecting survival of patients with colon and rectum cancer using competing risks model

Mohammad Reza Akhond; Anoshirvan Kazemnejad; Ebrahim Hajizadeh; Ali GhanbariMotlagh; Mohammad Reza Zali

Koomesh

Journal of Semnan University of Medical Sciences

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Comparison of influential factors affecting survival of patients with colon and rectum cancer using competing risks model

Author(s):

Mohammad Reza Akhond,

Anoshirvan Kazemnejad

^,*,

Ebrahim Hajizadeh,

Ali GhanbariMotlagh,

Mohammad Reza Zali

Koomesh:Vol. 12, issue 2; 119-128

Published online:Sep 25, 2010

Article type:Research Article

Received:Mar 07, 2010

Accepted:Aug 07, 2010

How to Cite:Mohammad Reza AkhondAnoshirvan KazemnejadEbrahim HajizadehAli GhanbariMotlaghMohammad Reza ZaliComparison of influential factors affecting survival of patients with colon and rectum cancer using competing risks model.koomesh.12(2):e153808.

Abstract

Introduction: Colorectal cancer is the most common cancer of digestive system and also fourth cause for death of cancer around the world. Different studies indicate that survival of patients suffering from colorectal cancer has recently developed in some areas of the world. However, it is not clear which factors involve in this improvement. This study aims at investigating some clinical and pathologic factors in prognosis of these patients with colon and rectum cancers separately. Material and Methods: Data recorded from 1194 patients with colorectal cancer in Cancer Record Center of Research Center for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences (Tehran, Iran) was used in this study. Data analysis was performed using competing risks model. Software used for data analysis was STATA, 11 version, and significance level was regarded as 0.05. Results: Body mass index, alcohol consumption, tumor site, inflammatory bowel disease, metastasis to lymph nodes and metastasis to other organs had significant effect on death of colon cancer, while body mass index, metastasis to other organs and kind of the first treatment had significant effect (P

Keywords

Colon cancer, Rectum cancer, Survival, Competing risks

سرطان کولون، سرطان رکتوم، بقا، ریسک‌های رقابتی

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