Radiation protective effect of green tea extract in mice irradiated with gamma rays

authors:

avatar Kourosh Saber 1 , avatar Mehrsa Majdaeen 2 , avatar Shiva Rahbar 1 , avatar Soheil Elmtalab 3 , avatar hamed zamanimanesh 1 , avatar Razzagh AbediFirouzjah 4 , *

Dept. of Medical Physics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Dept. of Radiotherapy and Oncology, Guilan University of Medical Sciences, Razi Hospital, Rasht, Iran
Dept. of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
- Dept. of Radiology Technology, School of Paramedical, Babol University of Medical Sciences, Babol, Iran

how to cite: Saber K, Majdaeen M, Rahbar S, Elmtalab S, zamanimanesh H, et al. Radiation protective effect of green tea extract in mice irradiated with gamma rays. koomesh. 2021;23(6):e154083. https://doi.org/10.5812/koomesh-154083.

Abstract

Introduction: The aim of this study was to investigate the radiation protective effect of daily oral consumption (for one week/one month) and single oral dose of green tea extract against gamma irradiation in mice. Materials and Methods: This study was performed on 60 adult male Balb/c mice weighing 25 to 30 gr in 6 equal groups. These groups include control, only irradiated, daily consumption of 200 mg/kg of green tea extract for one week and without irradiation, irradiated group after consumption of 200 mg/kg extract for one week, irradiation after 200 mg/kg oral consumption of green tea extract for one month, and irradiation 2 hours after eating 800 mg/kg of green tea extract. Results: The results demonstrated that the oral consumption of green tea extract before irradiation significantly decreased MnPCE (51% decrease, P