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The Effect of Cystoscopy on PSA Levels in Patients with Urologic Diseases
Authors
Bahar Bastani1, Ashkan Heshmatzade Behzadi2,*, Mohammad Amin Abbasi3, Jaleh Hassanloo3, Mahsa Sedaghati3, Yasamin Honarbakhsh3, Amir Poya Akasheh3, Mohsen Alghasi3, Parviz Rafiezadeh3, Maryam Masouminia3, Koosha Kamali3
1Nephrology Devision, Saint Louis University, USA
2Urology Department Research Center, Iran University of Medical Sciences and Health Services, ashkan_hbehzadi@yahoo.com, IR-Iran
3Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, IR-Iran
*Corresponding Author: Urology Department Research Center, Iran University of Medical Sciences and Health Services, ashkan_hbehzadi@yahoo.com, IR-Iran. Fax: 98-912-3582506. Email: ashkan_hbehzadi@yahoo.com
Published online:Jan 31, 2010
Article type:Research Article
Received:Apr 27, 2009
Accepted:May 30, 2009
How to Cite:Bastani B, Behzadi A, Abbasi M, Hassanloo J, Sedaghati M, et al. The Effect of Cystoscopy on PSA Levels in Patients with Urologic Diseases. Nephro-Urol Mon. 2010;2(1):. doi:
Abstract
Background and Aims: There is controversy on change of PSA levels after some urological procedures such as cystoscopy. In this study, we evaluated the effect of cystoscopy on PSA levels in patients with urologic diseases.
Methods: In a before-after study, 190 patients with urologic diseases such as relapsing UTI, urinary incontinency, hematuria, TCC follow up, DJ catheter removal and urinary retention were investigated. PSA levels were measured before and after cystoscopy.
Results: Mean age of patients was 6313 years. Mean duration of procedure was 2.51.2 minutes. Total PSA level increased in all groups after cystoscopy. More changes were found in patients with urinary retention (P<0.01). There was a relation between patients' ages and primary and secondary PSA levels (P=0.0001). Moreover there was a statistically significant direct relation between the PSA levels and the duration of procedures in different groups of patients (P=0.001).
Conclusion: Total PSA increases after cystoscopy and the level of PSA is higher in patients with urinary retention and change in level of PSA was higher in these patients. The results can have implications for the screening for prostate cancer patients.
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Copyright
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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