Albuminuria Predicts Kidney Function Outcome in Egyptian Essential Hypertensive Patients

How to Cite:Minshawy O, Osman A. Albuminuria Predicts Kidney Function Outcome in Egyptian Essential Hypertensive Patients. Nephro-Urol Mon. 2010;2(1):. doi:

Abstract

Background and Aims: Hypertension is both a cause and effect of renal impairment and its treatment influences kidney function outcome, interests in the study of albuminuriain hypertensivepatients has grown as it may represent a useful and relatively inexpensiveclinical tool for the identification of hypertensive patientsat higher risk for developing early renal impairment. In Egypt, hypertension is one of the most important causes of end stage renal disease (ESRD). The aim of the work is to identify albuminuria in Egyptian essential hypertensive patients, and its relation with kidney function outcome.

Material and Methods: Two hundred and forty one essential hypertensive patients, were included in a cross-section study for the presence of albuminuria and its relation to estimated glomerular filtration rate (eGFR); their history of hypertension ranges from 12-240 months with a mean of 75±54 (aged 48±11 years, range 20 - 76 years) any patient with doubtful history of essential hypertension were excluded from the study, patients included in the study were 148 (61%) males and 93 females, their mean body mass index was 27±5 kg/m².

Results: Prevalence of normoalbuminuria was 59%, microalbuminuria 31%, and macroalbuminuria 10%. eGFR was significantly decreased in microalbuminuria and macroalbuminuria groups, on further analysis this reduction in eGFR was not related to severity of hypertension but to its duration. There was a significant increase in the duration of history hypertension in eGFR < 60 ml/min/1.73 m² in comparison to eGFR > 60 ml/min/1.73 m² in all groups (Normo, Micro and Macroalbumiuria). There was no significant difference eGFR between controlled and uncontrolled groups (either by MDRD or Mayo clinic formula).

Conclusion: Albuminuria is a risk marker for prediction of the progression of nephropathy in Egyptian essential hypertensive patients and may reflect hypertensive injury to the kidney.

Keywords

Hypertension

Albuminuria

Glomerular filtration rate

Kidney function outcome

Full Text

Full text is available in PDF

A Reversible Syndrome of Acute Renal Failure Associated with Renin-Angiotensin Inhibitor Drugs

Anil K. Mandal

21

May

2016

Burden of Hypertension and Abnormal Glomerular Permeability in Hypertensive School Children

Adebukola B Ajite,

Theophilus A Aladekomo,

Temilade Aderounmu,

Wasiu A Olowu

9

Nov

2014

Association of Micro Albuminuria With Diastolic Function in Obese Normotensive No Diabetic Individuals

Farzanehsadat Minoo,

Mitra Mahdavi Mazdeh,

Mohamad Reza Abasi

13

Apr

2024

Relationship Between Hyperuricemia and Hypertension in Diabetic Patients Undergoing Hemodialysis

Anahita Arian,

Hamid Salehiniya,

Tina Erfani,

Vajehallah Raeesi

31

Jul

2010

Environmental Factors Incriminated in the Development of End Stage Renal Disease in El-Minia Governorate, Upper Egypt

Emad G. Kamel,

Osama El-Minshawy

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 1 week ago
Scopus by Title: 0
Last Update: 1 week ago
Scopus by Title (Ref): 0
Last Update: 1 week ago
CrossRef: 0
Last Update: 1 day ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

Osama Minshawy:[PubMed][Scholar]
Ashraf Osman:[PubMed][Scholar]

Outlines

Albuminuria Predicts Kidney Function Outcome in Egyptian Essential Hypertensive Patients

Abstract

Full Text

Similar Articles

A Reversible Syndrome of Acute Renal Failure Associated with Renin-Angiotensin Inhibitor Drugs

Burden of Hypertension and Abnormal Glomerular Permeability in Hypertensive School Children

Association of Micro Albuminuria With Diastolic Function in Obese Normotensive No Diabetic Individuals

Relationship Between Hyperuricemia and Hypertension in Diabetic Patients Undergoing Hemodialysis

Environmental Factors Incriminated in the Development of End Stage Renal Disease in El-Minia Governorate, Upper Egypt

Last Update: 1 week ago

Last Update: 1 week ago

Last Update: 1 week ago

Last Update: 1 day ago