Isolated intestinal Kaposi’s sarcoma in a kidney transplant patient: Diagnostic difficulty

Alina Betkowska Prokop; Ewa Ignacak; Marek Kuzniewski; Tomasz Kruszyna; Krzysztof Okon; Władysław Sułowicz

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Isolated intestinal Kaposi’s sarcoma in a kidney transplant patient: Diagnostic difficulty

Author(s):

Alina Betkowska Prokop¹,

Ewa Ignacak¹,

Marek Kuzniewski¹,

Tomasz Kruszyna²,

Krzysztof Okon³,

Władysław Sułowicz^1,*

1Department of Nephrology, Jagiellonian University, College of Medicine, Cracow, Poland

2Department of Gastrenterosurgery, Jagiellonian University, College of Medicine, Cracow, Poland

3Department of Pathology, Jagiellonian University, College of Medicine, Cracow, Poland

Nephro-Urology Monthly:Vol. 3, issue 3; e93972

Published online:Jun 30, 2011

Article type:Case Report

Received:May 18, 2019

Accepted:Jun 30, 2011

How to Cite:Alina Betkowska ProkopEwa IgnacakMarek KuzniewskiTomasz KruszynaKrzysztof OkonWładysław Sułowiczet al.Isolated intestinal Kaposi’s sarcoma in a kidney transplant patient: Diagnostic difficulty.Nephro-Urol Mon.3(3):e93972.

Abstract

A 33 year old man with unknown cause of end stage renal disease received a renal graft from a deceased donor. Triple immunosuppression with cyclosporine A (CyA), mycophenolate mofetil and prednisone was prescribed. Four months after transplantation the patient developed general weakness, fever, diarrhea and bleeding to the intestinal tract leading to severe anemia. Due to the fact that no bleeding site was found during gastroduodenoscopy and colonoscopy, open surgery was performed and revealed bleeding ulcerations in small intestine. Partial resection of small intestine and hemicolectomy was performed and histopathological examination revealed Kaposi’s sarcoma (KS) infiltration in the ulceration. CyA was withdrawn and rapamycine started. After 4 years post surgery the patient has been doing well, without symptoms of KS.

Keywords

Kidney transplantation

Immunosuppression

Kaposi’s sarcoma

Gastrointestinal hemorrhage

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