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Solid Pseudopapillary Tumor of Pancreas: Presentations and Management

Author(s):
Arash Mohammadi TofighArash Mohammadi TofighArash Mohammadi Tofigh ORCID1,*, Sh RahmaniSh Rahmani1, M MozaffarM Mozaffar2, SM AbdollahiSM Abdollahi3, B  Nemati HonarB Nemati Honar3
1Assistant Professor, Department of Surgery, Shahid Beheshti Uni- versity of Medical Sciences, Tehran, Iran
2AssociateProfessor, Department of Surgery, Shahid Beheshti Uni- versity of Medical Sciences, Tehran, Iran
3Resident, Department of Surgery, Shahid Beheshti Uni- versity of Medical Sciences, Tehran, Iran


Shiraz E-Medical Journal:Vol. 9, issue 3; 149-157
Published online:Jul 01, 2008
Article type:Research Article
Received:Oct 18, 2007
Accepted:Jun 15, 2008
How to Cite:Arash Mohammadi TofighSh RahmaniM MozaffarSM AbdollahiB Nemati HonarSolid Pseudopapillary Tumor of Pancreas: Presentations and Management.Shiraz E-Med J.9(3):149-157.

Abstract

Objectives:

To report a case series of pancreatic pseudopapillary solid cystic tumor as a rare low grade malignant abdominal tumor, which is relatively frequent in young women, with a discussion about its presentations and management to carry out a review of literature.

Materials and Methods:

We report a case series of 5 Solid pseudopapillary tumors of pancreas .Then all published series of this tumor since 1952 will be analyzed according to our series. The reviewed parameters included demographic data clinical manifestations, therapeutic modalities, and clinical outcomes.

Results:

Eighty percent of patients were female with mean age of 22.4 years. Two were presented with acute abdominal signs following blunt trauma, 2 with mass sensation, and 2 were incidentally found. They were all diagnosed pre-operatively through computed tomographic (CT) scan and all tumors had benign characteristics. No abnormalities were found in the follow up period and control CT scans.

Conclusion:

Solid pseudopapillary tumors of pancreas have benign behavior, and the treatment of choice consists of surgical resection. It may spread outside the pancreas, particularly in peritoneal cavity. Metastatic spread may be promoted by trauma, including tumor biopsies, which should never be performed. The outcome after surgical resection is excellent with 90% survival in the long term. Recurrence has been reported in approximately 10% of patients.

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