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Does Pregnancy actually affect serum calcium and inorganic phosphate levels?
Authors
Ikaraoha Chidiebere Ikechukwu1,*, Usoro Chinyere A.O2, Igwe Chidi Uzoma3, Nwobu Gilbert O3, Mokogwu Azukaego Thomas Hughs1, Okwara John Ekenedirichukwu4, Ukaegbu Queeneth O3
1Department. of Chemical Pathology, School of Clinical Medicine, Igbinedion University, Okada, Edo State, Nigeria.
2Department of Chemical Pathology, College of Medicine, University of Calabar, Nigeria.
3Department. of Medical Laboratory Sciences, College Of Medicine, Ambrose Alli University, Ekpoma, Nigeria.
4Department of Chemical Pathology, College Medicine, University of Ibadan, Ibadan, Nigeria.
*Corresponding Author: Deptartment of Chemical Pathology, School of Clinical Medicine, College of Health Sciences, Igbinedion University Okada, Edo State,Nigeria, [email protected]. Email: [email protected]
Published online:Apr 04, 2005
Article type:Research Article
Received:Oct 14, 2004
Accepted:Dec 20, 2004
How to Cite:Ikechukwu IC, A.O UC, Uzoma IC, Gilbert O N, Thomas Hughs MA, et al. Does Pregnancy actually affect serum calcium and inorganic phosphate levels?. Shiraz E-Med J. 2005;6(1 and 2):31836. doi:
Abstract
The serum level of calcium and inorganic phosphate in pregnancy is less well defined among Black Nigerians, than among Caucasians. This case control study assessed the relation of serum calcium and inorganic phosphate concentrations to pregnancy in Nigerian women. Blood samples were collected by venepuncture technique from 128 pregnant women during their first, second and third trimesters. A total of 72 non pregnant women were recruited as controls. Serum calcium and inorganic phosphate levels were determined. Pregnant women had significantly lower serum levels of calcium and inorganic phosphate compared to controls (P<0.000 and P<0.001) respectively. There was a statistically significant progressive decrease in serum calcium and inorganic phosphate concentration from first trimester to third trimester (P<0.000 and P<0.001) respectively. Serum calcium and inorganic phosphate may be reduced during pregnancy due to inadequate dietary intake. The decrease in serum calcium and inorganic phosphate levels parallels increase in gestational age. This may result from mineral transfer from mother to developing fetus.
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© 2005, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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