Laboratory Diagnosis of Myeloperoxidase Deficiency: A Case Report.

authors:

avatar Zahra Pourmehdi 1 , avatar Seyedkamaleddin Tabatabaei 2 , avatar Seyedahmadreza Salimbahrami 1 , * , avatar Shiva Borzouei 3

Professor, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences
Clinica Fellow, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences
Research Assistant, Hematology and Oncology Resarch Center, Tabriz University of Medical Sciences

how to cite: Pourmehdi Z, Tabatabaei S, Salimbahrami S, Borzouei S. Laboratory Diagnosis of Myeloperoxidase Deficiency: A Case Report.. Shiraz E-Med J. 2012;13(1):e93925. 

Abstract

Myeloperoxidase deficiency is a common disorder featuring deficiency, either in quantity or function of Myeloperoxidase. The patients are misdiagnosed because majority of individuals with Myeloperoxidase deficiency show no signs of immunodeficiency. Myeloperoxidase defi-ciency is noted even before the diagnosis is suspected because the machines that perform automated leukocyte differential counts rely upon neutrophil Myeloperoxidase activity to enumerate these cells. This report describes two cases of myeloperoxidase deficiency that were diagnosed after reassess of the hemograms.In one case ,we got to the diagnosis after the patient went under Bone marrow Aspiration for ruling out leukemia.

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