Abstract
Background: Skin wound healing is very significant physiological procedure. It is quite obvious that promoting this healing is important too. One of the most popular compounds used ever for skin care is Vaccinium arctostaphylos essential oil. In this study we tried to compare the effects of V. arctostaphylos and zinc oxide on secondary intentioned open-wound healing in rats.
Materials and Methods: In this experimental study, 75 male rats included in 5 groups: eucerin, zinc oxide, Vaccinium extract 10 and 20%, not treated. The whole operation was taking place under general anesthesia circumstances. Took photos continuously 21 days after wound creation and catch biopsy intervals were 3, 7, 14 and 21 days. Wounds areas are measured by Scion Image ™ software. At last, all data were analyzed using SPSS-17.
Results: As a result V. arctostaphylos with dose of 20% has significant healing properties compared to zinc oxide. These data were validating under confidence surface of 99% (p<0.01).
Conclusion: Base on earned data it will be suitable to use of zinc oxide ointment for healing reason but there is opportunity to researcher to survey higher dose of this plant extraction in contrast of zinc oxide.
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© 2014, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.