Cognitive Impairment in Multiple Sclerosis

Mohammad Ali Sahraian; Farnaz Etesam

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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Cognitive Impairment in Multiple Sclerosis

Author(s):

Mohammad Ali Sahraian¹,

Farnaz Etesam^1,*

1Department of Neurology, Sina MS Research Center, Tehran University of Medical Sciences, Tehran, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 1; 1-7

Published online:Mar 12, 2013

Article type:Review Article

Received:May 27, 2012

Accepted:Aug 12, 2012

How to Cite:Mohammad Ali SahraianFarnaz EtesamCognitive Impairment in Multiple Sclerosis.Zahedan J Res Med Sci.16(1):1-7.

Abstract

Cognitive impairment can emerge in the earliest phases of multiple sclerosis. It strongly impacts different aspects of Multiple Sclerosis (MS) patients' lives, like employment, social relationships and the overall quality of life; thus, its on-time recognition and treatment is mandatory. This paper discusses issues, diagnostic methods and treatment options for cognitive dysfunctions in MS. This paper is a descriptive review of the related studies in the recent 10 years, performing a keyword search in the main databases. Cognitive impairment mostly involves aspects of information processing, memory and executive functioning in MS. Neuropsychological tests like MACFIMS and BRB-N are recommended for its assessment. Still, there is no fully efficient treatment for cognitive impairment. Researchers have shown some positive effects, using disease-modifying therapies and cognitive rehabilitation. Depression, pain, fatigue and other factors influencing cognitive functions must be paid attention to. Recognizing cognitive impairment as a major symptom for MS, makes studying this subject one of the priorities in dealing with the disease. Therefore, a consecutive research for identification and management of this part of quality of life in MS patients is obligatory.

Keywords

Multiple sclerosis

Cognitive impairment

Cognitive

Neuropsychological test

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