Comparison of Serum CRP in Migraine Sufferers and Normal Population

Hosseinali Salehi; Mohammad Aminianfar; Alireza  Ranjbar-Naeeni; Aliasghar Saidi; Fariba Rastgoo

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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Comparison of Serum CRP in Migraine Sufferers and Normal Population

Author(s):

Hosseinali Salehi¹,

Mohammad Aminianfar^1,*,

Alireza Ranjbar-Naeeni¹,

Aliasghar Saidi²,

Fariba Rastgoo³

1Department of Neurology, AJA University of Medical Sciences, Tehran, Iran

2Department of Infectious and Tropical disease, AJA University of Medical Sciences, Tehran, Iran

3General Physician, Tehran, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 1; 13-16

Published online:Jan 27, 2013

Article type:Research Article

Received:Apr 26, 2012

Accepted:Jul 12, 2012

How to Cite:Salehi H, Aminianfar M, Ranjbar-Naeeni A, Saidi A, Rastgoo F. Comparison of Serum CRP in Migraine Sufferers and Normal Population.Zahedan J Res Med Sci.2013;16(1):13-16.

Abstract

Background: CRP (C-reactive protein) is one of the known inflammatory markers in the body. Studies claim that the level of this marker in patients with migraine is higher than normal peoples. Despite the result of various studies, even the relation between serum CRP and migraine is not detected thoroughly and is in a halo of ambiguity, therefore in this study, we intended to assess the relation between migraine and serum CRP levels.

Patients and Methods: The present study was performed as a case-control on 47 migraines suffers that presented Besat hospital on year 2011, at intervals between their attacks and 50 normal individuals. Serum CRP level was measured at interval between attacks or at least 72 hour after the completion of the last attack and was compared with obtained results from normal population.

Results: The comparison of CRP level in two groups, indicated that the median CRP at case group was 16.40 mg/dl and at control group 9.76 mg/dl (p≤0.05). The comparison of CRP median between the sufferers of classic migraine, migraine without aura and individuals without migraine, indicated that the CRP median difference at without aura migraine sufferers and normal population was not meaningful, but classic migraine suffers had higher serum CRP level than the other two groups.

Conclusions: Finally, we should stay that the present study demonstrate that CRP inflammatory marker was higher at migraine suffers in comparison with normal general population and could explained the role of inflammation in creation and progression of this type of headache.

Keywords

Department of Infectious

Disease

AJA University of Medical Sciences

Tehran

Iran

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Author(s):

Hosseinali Salehi:[PubMed][Scholar]
Mohammad Aminianfar:[PubMed][Scholar]
Alireza Ranjbar-Naeeni:[PubMed][Scholar]
Aliasghar Saidi:[PubMed][Scholar]
Fariba Rastgoo:[PubMed][Scholar]