Prevalence of Primary Open Angle Glaucoma in Obstructive Sleep Apnea Syndrome

authors:

avatar Masoud Reza Manaviat 1 , avatar Mohammad Raza Besharati 2 , * , avatar Ali Reza Azarpeikan 3 , avatar Abolhasan Halvani 4 , avatar Parisa Khani 5 , avatar Alimohammad Abdoli 6 , avatar Elahe Abbasi - Shavvazi 7

Department of Ophthalmology, Geriatric Ophthalmology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Ophthalmology, Geriatric Ophthalmology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Ophthalmology, Geriatric Ophthalmology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Andorra
General Physician , Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
General Physician , Geriatric Ophthalmology Research Center, Shahid Sadoughi University of Medical Sciences, , Yazd, Iran
General Physician , Geriatric Ophthalmology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Zahedan Journal of Research in Medical Sciences: Vol.16, issue 1; 44-47
published online: April 15, 2013
article type: Research Article
received: January 24, 2013
accepted: February 28, 2013

How To Cite Manaviat M R, Besharati M R, Azarpeikan A R, Halvani A, Khani P, et al. Prevalence of Primary Open Angle Glaucoma in Obstructive Sleep Apnea Syndrome. Zahedan J Res Med Sci. 2014;16(1): 44-47. 

Abstract

Background: Obstructive sleep apnea (OSA) is partial or complete recurrent upper airway obstructions during sleep. Reduction in blood flow of the optic nerve head is an important causative factor in glaucoma. The objective of this study is to determine the prevalence of primary open angle glaucoma (POAG) in OSA patients.
Patients and Methods: From September 2009 to January 2010 in this descriptive-analytic cross sectional study, 90 cases of patients with OSA referred to Yazd Shahid Sadoughi hospital were collected and studied by polysomnography, blood gas analysis and ocular examination including measurement of intra ocular pressure, gonioscopy, fondoscopy and automated perimetry. Statistical analysis was performed by SPSS software.
Results: Thirty-one patients had mild OSA, 30 patients had moderate OSA and 29 patients had severe OSA. The prevalence of POAG in this group of patients was 10% (95% CI: 4-16). It is higher than the general population in the same age group (p=0.017). There was no significant correlation between the presence of glaucoma and apnea hypopnea index (AHI), mean saturation arterial O2 (MSaO2), body mass index (BMI), sex and age. A significant correlation between AHI with IOP and cup/disc ratio was not documented.
Conclusions: According to our founding, the prevalence of POAG in OSA patients was higher than the general population in the same age group. Thus we recommend screening of glaucoma in OSA patients. This Study suggests that AHI, MSaO2, BMI, sex or age are not important risk factors for glaucoma in OSA patients.

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