Physical Activity and Obesity Related Hormones


avatar Pouran Makhdoumi 1 , avatar Mehdi Hedayati 2 , * , avatar Marjan Zarif-Yeganeh, 2

Department of Toxicology, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran
Cellular and Molecular Research Center, Rese arch Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

how to cite: Makhdoumi P, Hedayati M , Zarif-Yeganeh, M . Physical Activity and Obesity Related Hormones. Zahedan J Res Med Sci. 2014;16(8): -.


Probably, obesity can be considered as the most common metabolic disorder. In other words, the control of metabolism is disrupted in this condition. The most important metabolic control is performed by hormones. Today, adipose tissue is considered as an active tissue in secretion of hormones. In obesity, in addition to adipose tissue hormones, effective neuropeptides on appetite are interfered. There are 4 main approaches in the management and treatment of obesity including nutrition and diet therapy, physical activity, medical and surgical approaches. The specialists and obese patients prefer the first and second approaches. Physical activity helps to control and treat this disorder by influencing on obesity-related hormones. The main obesity-related hormones are ghrelin, agouti, obestatin, leptin, adiponectin, nesfatin, visfatin, tumor necrosis factor, interleukin-6, and resistin. In this review, the effect of physical activity on 10 major obesity-related hormones has been discussed.


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