The Effect of Eccentric Exercise on Total Anti-Oxidant Capacity, Reduced Glutathione and Malondialdehyde Levels in Active Women

Parichehr Hanachi; Afsaneh Shemshaki; Sekineh  Norouziyan

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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The Effect of Eccentric Exercise on Total Anti-Oxidant Capacity, Reduced Glutathione and Malondialdehyde Levels in Active Women

Author(s):

Parichehr Hanachi¹,

Afsaneh Shemshaki²,

Sekineh Norouziyan^3,*

1Tehran , Iran

2Department of Physical Education, Faculty of Physical Education and Sport Sciences, Alzahra University, Tehran, Iran

3Department of Physical Education , Alzahra University, Qaemshahr, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 6

Published online:Feb 23, 2013

Article type:Research Article

Received:Jul 31, 2012

Accepted:Oct 18, 2012

How to Cite:Hanachi P, Shemshaki A, Norouziyan S. The Effect of Eccentric Exercise on Total Anti-Oxidant Capacity, Reduced Glutathione and Malondialdehyde Levels in Active Women.Zahedan J Res Med Sci.2013;16(6):null-null.

Abstract

Background: Although exercise can increase free radicals by generating oxidative stress, it also can decrease them by increasing the antioxidant enzymes in the body as well. The purpose of this study is to investigate the eccentric activity on some oxidative and anti-oxidative factors pertaining to blood plasma of PE women immediately after the exercise.

Materias and Methods: Sixteen female students have been volunteered in this study randomly divided into two groups including eccentric training group and control group. The blood samples were drawn from the subjects one hour before and immediately after the exercise to measure the reduced Glutathione (GSH), Malondialdehyde (MDA) and total anti-oxidant capacity (TAC) levels. The data were analyzed by SPSS-13 software using the one-way analysis of variance, one-way ANOVA test, (to determine the differences between groups) at the confidence level of 90% (p<0.05).

Results: The results has shown that the TAC, MDA, GSH levels after the eccentric exercise increased significantly compared to pre-exercise (p=0.001, p=0.001, p=0.033). The GSH and MDA levels also after the eccentric exercise were significantly higher than the pre-exercise compared to control group.

Conclusion: It seems that sever eccentric exercise is an important stimulus making significant changes in body’s anti-oxidative system and has the ability to improve the anti-oxidant capacities too.

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Author(s):

Parichehr Hanachi:[PubMed][Scholar]
Afsaneh Shemshaki:[PubMed][Scholar]
Sekineh Norouziyan:[PubMed][Scholar]