Antioxidant and Antibacterial Activity of Various Extracts of Malcolmia africana (L.) R. Br

Akbar  Esmaeili; Leila Moaf; Shamsali Rezazadeh; Mhedi Ayyari

Zahedan Journal of Research in Medical Sciences

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Antioxidant and Antibacterial Activity of Various Extracts of Malcolmia africana (L.) R. Br

Author(s):

Akbar Esmaeili^1,*,

Leila Moaf²,

Shamsali Rezazadeh³,

Mhedi Ayyari⁴

1Department of Chemical Engineering, North Tehran Branch, Islamic Azad University, Tehran, Iran

2Department of Chemical Engineering, North Tehran Branch, Islamic Azad University, Tehran, Iran

3Iranian Academic Center for Education, Culture and Research, Institute of Medicinal Plant Research, Tehran, Iran

4Iranian Academic Center for Education, Culture and Research, Institute of Medicinal Plant Research, Tehran, Andorra

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 3; 6-11

Published online:Jan 28, 2013

Article type:Research Article

Received:Sep 29, 2012

Accepted:Nov 11, 2012

How to Cite:Akbar EsmaeiliLeila MoafShamsali RezazadehMhedi AyyariAntioxidant and Antibacterial Activity of Various Extracts of Malcolmia africana (L.) R. Br.Zahedan J Res Med Sci.16(3):6-11.

Abstract

Background: Antioxidants are compounds that protect the body against cell membrane injury or damage to the cell’s genetic material from free radical activity. The objective of this research was to study the antioxidant and antibacterial activities of various extracts from the seeds and aerial parts of Malcolmia africana (L.) R. Br.

Patients and Methods: The overall results of M. africana tests allowed us to study the various extracts [hexane extract (HE), methanol extract (ME) and chloroform extract (CE)] of the test total phenolic, ABTS [(2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid))] and DPPH (2, 2-diphenyl-1-picryl hydrazyl) and also to test β-carotene, largest property antioxidant. The antimicrobial activity of the extracts of both samples was determined against seven Gram-positive and Gram-negative bacteria.

Results: The amount of total phenolics was highest in the methanol extract (ME) of the seeds (225.19±0.02) and aerial parts (208.52±0.012 mg) Gallic acid/gr sub-fractions. The property antioxidant shows both of the mechanisms of electron transfer and the hydrogen transfer which the extracts has gone through.

Conclusion: This investigation showed that ME has the highest antioxidant behavior. The antimicrobial activities of the extracts of both samples were determined against seven Gram-positive and Gram-negative bacteria. The bioassay shows that the seeds and aerial parts exhibit moderate antimicrobial activity. Therefore, the extracts could be suitable as antimicrobial and anti-oxidative agents in the food industry.

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