Primary Lung Cancer Subtypes:  H ow Does Chest CT Scan Help to Differentiate  them?

Payam Mehrian; Leila Mosadegh; Mihan  Poorabdollah

Zahedan Journal of Research in Medical Sciences

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Primary Lung Cancer Subtypes: H ow Does Chest CT Scan Help to Differentiate them?

Author(s):

Payam Mehrian¹,

Leila Mosadegh²,

Mihan Poorabdollah^3,*

1Department of R adiology , Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases ( NRITLD ) , Shahid Beheshti University of Medical Sciences, Tehran, Iran

264 Zahedan Journal of Research in Medical Sciences Journal homepage: www.zjrms.ir Primary Lung Cancer Subtypes: H ow Does Chest CT Scan Help to Differentiate them? Payam Mehrian, 1 Leila Mosadegh, 1 M i h a n Poorabdollah* 1 1 . Department of R adiology , Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases ( NRITLD ) , Shahid Beheshti University of Medical Sciences, Tehran, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 1; 64-68

Published online:Sep 01, 2013

Article type:Research Article

Received:Feb 09, 2013

Accepted:May 01, 2013

How to Cite:Payam MehrianLeila MosadeghMihan PoorabdollahPrimary Lung Cancer Subtypes: H ow Does Chest CT Scan Help to Differentiate them?.Zahedan J Res Med Sci.16(1):64-68.

Abstract

Background: Lung cancer has wide variety of clinical presentations and different imaging features relating its subtypes. This study is focused on the role of CT scan in differentiating primary lung cancer subtypes including adenocarcinoma, squamous cell carcinoma and small cell carcinoma.

Materials and Methods: This retrospective study is conducted on 55 pathologically diagnosed primary lung cancer patients. Several CT features including lung mass and pleural effusion and parenchymal nodule characteristics, mediastinal and hilar involvement, pericardial effusion and thickening, chest wall invasion, reticulation, superior vena cava (SVC) syndrome and encasement of main bronchus were checked.

Results: We enrolled 55 primary lung cancer patients including 29 adenocarcinomas, 19 squamous cell carcinomas and 7 small cell carcinomas, 36 males and 19 females with mean age of 60.3 years. Most common CT features of primary lung cancer were lung mass (94.5%) particularly located in hilum (51.9%) and irregular bordered (55.8%). Other prevalent findings included parenchymal nodules (60%), pleural effusion (41.8%), mediastinal adenopathy (47.3%), hilar adenopathy (42.9%), mediastinal invasion (43.6%) and reticulation (56.4%). Hilar adenopathy (47.4%), reticulation (48.3%) and parenchymal nodule (62.1%) in adenocarcinoma; hilar mass (57.9%) and parenchymal nodule (68.4%) in squamouos cell carcinoma; hilar and mediastinal involvement in small cell carcinoma were the most frequent findings.

Conclusions: Comparing three subtypes, we found squamous cell and adenocarcinoma more similar regarding CT images parenchymal nodules, mass calcification and cavitation were more frequently seen in them compared to small cell lung cancer whereas hilar involvement, mediastinal involvement, irregular bordered mass and encasement of main bronchus were more prevalent in small cell carcinoma.

Keywords

Adenocarcinoma

Small Cell Carcinoma Squamous Cell Carcinoma

CT Scan

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