Effects of Supplementation of Turmeric Extract on Balance Antioxidant- Prooxidant Spleen and Heart Tissues in Rats Exposed to Lead

sadeq saberi; parvin farzanegi; Shima Ranjbar; Ahmad Gholizade; Jalil Jafari; Hadis Saberi; Amin Talebolhagh-Kakhki

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

Current Issue All Issues In Press Articles Accepted Manuscripts Search

Journal Information Boards and Committees Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support Reviewer and AE Registration Form

APC

Authors Guide Submit Manuscript

Effects of Supplementation of Turmeric Extract on Balance Antioxidant- Prooxidant Spleen and Heart Tissues in Rats Exposed to Lead

Author(s):

sadeq saberi^1,*,

parvin farzanegi²,

Shima Ranjbar¹,

Ahmad Gholizade³,

Jalil Jafari⁴,

Hadis Saberi⁵,

Amin Talebolhagh-Kakhki²

1MSc of Exercise Physiology, Education of Golestan, Golestan, Iran

2Department of Exercise Physiology, Faculty of Human Sciences, Azad University of Sari, Sari, Iran

3Department of Physical Education, Birjand University, Birjand, Iran

4Department of Exercise Physiology, Faculty of Physical Education, Shahid Rajaee University, Tehran, Iran

5MA of Mathematical, Teacher Training University of Sabzevar, Sabzevar, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 11; e92802

Published online:Jan 30, 2013

Article type:Research Article

Received:May 27, 2012

Accepted:Jul 19, 2012

How to Cite:sadeq saberiparvin farzanegiShima RanjbarAhmad GholizadeJalil JafariHadis SaberiAmin Talebolhagh-Kakhkiet al.Effects of Supplementation of Turmeric Extract on Balance Antioxidant- Prooxidant Spleen and Heart Tissues in Rats Exposed to Lead.Zahedan J Res Med Sci.15(11):e92802.

Abstract

Background : One of today's environmental crisis that industrial technology it produces. Lead is one of the most important environmental contaminants that prolonged contact with the production of free radicals. Study results show that air pollution is increases mortality due to cardiovascular disease.
Materials and Methods : To study the effects of consumption turmeric extracts on prooxidant- antioxidant balance of rats' spleen and heart tissues exposed to lead acetate. Thirty-six male rats randomly were classified into four groups as: 1) Basic, 2) Sham (turmeric solvent), 3) Lead, 4) turmeric extract+lead, (each group includes 9 rats). turmeric supplements were injected three times per week and total of 8 weeks to 30 mg/kg body weight. Injection protocol lead and turmeric extract or solvent (ethyl first) three sessions a week and will run for 8 weeks, all injections were in peritoneally.
Results : After separation of spleen and heart tissues and homogenization, showed injection of lead increases the index of lipid peroxidation in spleen and heart tissues. Also turmeric supplementation inhibits oxidative effects on the spleen and heart.
Conclusion : Based on this research findings using a healthy style, and herbal supplements is effective in reducing the harmful effects anti-oxidation pollutants.

Keywords

Fulltext

The full text of this article is available on the PDF file.

References

1.
The References of this article are available on the PDF file.

comments