Serum Uric Acid Level in Patients with Parkinson Disease

Authors

Farhad Iranmanesh1,*, Faranak Gadri2, Hamid Bakhshi3, Samira Sarhadi4
1Department of Neurology, Neuroscience Research Center, Kerman University of Medical Science, Kerman, Iran
2General Physician, Kerman University of Medical Sciences, Kerman, Iran
3Department of Medical Statistics, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
4General Physician, Kerman, Iran
*Corresponding Author: Department of Neurology, Neuroscience Research Center, Kerman University of Medical Science, Kerman, Iran Email: [email protected]

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 9; e92844
Published online:Oct 17, 2012
Article type:Research Article
Received:Jan 25, 2012
Accepted:Apr 15, 2012
How to Cite:Iranmanesh F, Gadri F, Bakhshi H, Sarhadi S. Serum Uric Acid Level in Patients with Parkinson Disease. Zahedan J Res Med Sci. 2013;15(9):e92844. doi:

Abstract

Background : Parkinson disease is one of the most prevalent degenerative nervous system diseases. Some recent studies show the possible effects of uric acid on this disorder. The aim of this study was to evaluate serum level of uric acid in patients with Parkinson disease.
Material & Methods : Serum uric acid were determined in 50 patients with Parkinson's disease and compared with 50 healthy persons, which were matched with age and sex. Data were analyzed with software SPSS-16 and statistical descriptive methods (mean-percentage, SD) and t-test.
Results : In this study, 26 men (52%) and 24 women (48%) were evaluated. The mean serum uric acid in patients was 4.79±1.21 and in the control group was 5.85 ±1.41. This difference was statistically significant (p≤0.001). Also, the mean serum uric acid in both men (4.87±1.20) and women (4.7±1.23) in patients group was statistically lower than both men (5.42±1.25) and women (5.91±1.62) in control group (p≤0.001).
Conclusion : The findings of this study show that low serum uric acid increase the risk of Parkinson's disease.

Highlights

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References

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Copyright

© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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