Serum Uric Acid Level in Patients with Parkinson Disease

Farhad  Iranmanesh; Faranak Gadri; Hamid Bakhshi; Samira Sarhadi

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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Serum Uric Acid Level in Patients with Parkinson Disease

Author(s):

Farhad Iranmanesh^1,*,

Faranak Gadri²,

Hamid Bakhshi³,

Samira Sarhadi⁴

1Department of Neurology, Neuroscience Research Center, Kerman University of Medical Science, Kerman, Iran

2General Physician, Kerman University of Medical Sciences, Kerman, Iran

3Department of Medical Statistics, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

4General Physician, Kerman, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 9; e92844

Published online:Oct 17, 2012

Article type:Research Article

Received:Jan 25, 2012

Accepted:Apr 15, 2012

How to Cite:Farhad IranmaneshFaranak GadriHamid BakhshiSamira SarhadiSerum Uric Acid Level in Patients with Parkinson Disease.Zahedan J Res Med Sci.15(9):e92844.

Abstract

Background : Parkinson disease is one of the most prevalent degenerative nervous system diseases. Some recent studies show the possible effects of uric acid on this disorder. The aim of this study was to evaluate serum level of uric acid in patients with Parkinson disease.
Material & Methods : Serum uric acid were determined in 50 patients with Parkinson's disease and compared with 50 healthy persons, which were matched with age and sex. Data were analyzed with software SPSS-16 and statistical descriptive methods (mean-percentage, SD) and t-test.
Results : In this study, 26 men (52%) and 24 women (48%) were evaluated. The mean serum uric acid in patients was 4.79±1.21 and in the control group was 5.85 ±1.41. This difference was statistically significant (p≤0.001). Also, the mean serum uric acid in both men (4.87±1.20) and women (4.7±1.23) in patients group was statistically lower than both men (5.42±1.25) and women (5.91±1.62) in control group (p≤0.001).
Conclusion : The findings of this study show that low serum uric acid increase the risk of Parkinson's disease.

Keywords

Uric acid

Parkinson

Gender

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References

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