Sonographic Evaluation of Mean Carotid Intima-Media Thickness of Patients with Moderate to Severe Non-Alcoholic Fatty Liver Disease

Sharereh Sanei Sistani; Mohammad Ali Elahifar; saeed javadi nodehi; Alireza Ansari-Moghaddam

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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Sonographic Evaluation of Mean Carotid Intima-Media Thickness of Patients with Moderate to Severe Non-Alcoholic Fatty Liver Disease

Author(s):

Sharereh Sanei Sistani¹,

Mohammad Ali Elahifar¹,

saeed javadi nodehi^2,*,

Alireza Ansari-Moghaddam³

1Department of Radiology, Zahedan University of Medical Sciences, Zahedan, Iran

2Resident of Radiology, Zahedan University of Medical Sciences, Zahedan, Iran

3Department of Epidemiology, Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 9; e92845

Published online:May 20, 2013

Article type:Research Article

Received:Jun 14, 2012

Accepted:Aug 24, 2012

How to Cite:Sharereh Sanei SistaniMohammad Ali Elahifarsaeed javadi nodehiAlireza Ansari-MoghaddamSonographic Evaluation of Mean Carotid Intima-Media Thickness of Patients with Moderate to Severe Non-Alcoholic Fatty Liver Disease.Zahedan J Res Med Sci.15(9):e92845.

Abstract

Background : Nonalcoholic fatty liver disease is a highly prevalent condition that is strongly associated with obesity, type II diabetes, and dyslipidemia. The purpose of this study is to investigate mean common carotid artery intima-media thickness as a marker of atherosclerosis in moderate to severe nonalcoholic fatty liver patients in comparison with control group.
Materials and Methods : In this study, the mean common carotid artery intima-media thickness (CCIMT) and other cardiovascular risk factors were measured in 39 nonalcoholic fatty liver patients and 39 control subjects. All were selected from general population in Zahedan. Then, the data were analyzed using χ² and independent t-tests.
Results : The results showed that nonalcoholic fatty liver patients had significantly higher common carotid intima-media thickness, waist circumference, waist/hip ratio, body mass index, triglyceride, total cholesterol (p=0.001), ALT (p=0.04), ALP (p=0.048), compared with the control group.
Conclusion : Nonalcoholic fatty acid liver patients are at significantly higher risk for atherosclerosis and cardiovascular diseases. Therefore, all of these patients should be evaluated for common carotid intima-media thickness and other cardiovascular risk factors.

Keywords

Atherosclerosis

Arterial intima

Nonalcoholic fatty liver disease

Cardiovascular diseases

Metabolic syndrome X

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