The Effect of Gundelia Tournefortii Hydro-Alcoholic Extract on Sperm Motility and Testosterone Serum Concentration in Mice

Mahboobeh Tabibian; Sima  Nasri; Parisa Kerishchi; Gholamreza Amin

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

Current Issue All Issues In Press Articles Accepted Manuscripts Search

Journal Information Boards and Committees Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support Reviewer and AE Registration Form

APC

Authors Guide Submit Manuscript

The Effect of Gundelia Tournefortii Hydro-Alcoholic Extract on Sperm Motility and Testosterone Serum Concentration in Mice

Author(s):

Mahboobeh Tabibian¹,

Sima Nasri^1,*,

Parisa Kerishchi²,

Gholamreza Amin³

1Department of Biology, Payam-e-Noor University, Tehran, Iran

2Department of Biology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran

3Department of Pharmacognosy, Faculty of Pharmacology, Tehran University, Tehran, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 8; e92898

Published online:Dec 30, 2012

Article type:Research Article

Received:Nov 20, 2011

Accepted:Jan 15, 2012

How to Cite:Mahboobeh TabibianSima NasriParisa KerishchiGholamreza AminThe Effect of Gundelia Tournefortii Hydro-Alcoholic Extract on Sperm Motility and Testosterone Serum Concentration in Mice.Zahedan J Res Med Sci.15(8):e92898.

Abstract

Background: Gundelia tournefortii was used as a food and medicinal in human life from
past time. The present study has been investigated the effects of Gundelia tournefortii on
number and motility of sperms and testosterone serum concentration.
Materials and Methods: In this experimental study, male mice were divided into control
and 4 experimental groups (Gundelia tournefortii extract at doses of 100, 200, 400, 800
mg/kg was administered intraperitoneally for 14 days). One week after the last injection,
blood samples were collected for hormonal assay. Also weight of testes, motility rate and
number of sperms were assessed. Data analysis was performed using one-way ANOVA
followed by Tukey test.
Results: Studies showed the number of sperms increased significantly at dose of 400
mg/kg (2.88±0.4580) (p=0.001).The percentage of sperm motility (p=0.001) and the
testicular weight (p=0.012) significantly increased at doses of 200 (36.83± 1.2506) and
400 mg/kg (57.51±2.1113) (p=0.001). Testosterone serum level significantly increased at
doses of 100 (p=0.05), 200 (p=0.05) and 400 mg/kg (p=0.001) as compared to control
group.
Conclusion: Gundelia tournefortii extract increases the number, motility of sperm and
testosterone level because of antioxidant components for example Quercetin presumably.

Keywords

Gundelia tournefortii extract

Sperm

Testosterone

Male mice

Fulltext

The full text of this article is available on the PDF file.

References

1.
The References of this article are available on the PDF file.

comments