Investigation between Alcoholic Extract and Essential Oil Melissa Officinalis L. New in Growth Inhibition of E. coli

Nooshin Naghsh; monir doudi; Zohreh  Nikbakht

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

Current Issue All Issues In Press Articles Accepted Manuscripts Search

Journal Information Boards and Committees Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support Reviewer and AE Registration Form

APC

Authors Guide Submit Manuscript

Investigation between Alcoholic Extract and Essential Oil Melissa Officinalis L. New in Growth Inhibition of E. coli

Author(s):

Nooshin Naghsh¹,

monir doudi²,

Zohreh Nikbakht^2,*

1Department of Biology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran

2Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 8; e92907

Published online:Dec 30, 2012

Article type:Research Article

Received:Aug 16, 2011

Accepted:Dec 13, 2011

How to Cite:Nooshin Naghshmonir doudiZohreh NikbakhtInvestigation between Alcoholic Extract and Essential Oil Melissa Officinalis L. New in Growth Inhibition of E. coli.Zahedan J Res Med Sci.15(8):e92907.

Abstract

Background: Therapy of plant is not any side effects and drug resustant for inhibition of
disease in world. In this study, antimicrobial effects of Melissa officinalis L. ethanol
exteract and essential oil on E. coli have been investigated.
Materials and Methods: In this investigation, diameter of inhibitory zone of these
materials was measured in disk agar diffusion method. Therefore, Melissa officinalisL.
ethanolic exteract (80%) and essential oil have been supplied. Then, antimicrobial activity
these substances next for 24 hour for ethanol extraction 80% concentration 50 to 1000
mg/mL and essential oil concentration with 3% to 100% has been considered. Also,
comparison of mean diameter of inhibitory zone between treatment and control groups of
ANOVA has been used.
Results: Results of these investigations were shown that extract ethanol Melissa officinalis
L. was any inhibitory effect on E. coli growth 24 hour after of treatment. Also, diameter of
inhibitory zone for 100% essential oil have been 33.2±0.13mm in E. coli that has been
increased in comparison control groups significantly (p=0.001). This inhibitory effects was
more than cefixime and cefteriaxone (p=0.00, p=0.01).
Conclusion: These found were shown that this plant prevents growth of E. coli In vitro
condition. This essential oil could be suggested as antimicrobial agents for inhibition of
bacterial diseases in human.

Keywords

Fulltext

The full text of this article is available on the PDF file.

References

1.
The References of this article are available on the PDF file.

comments