The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats

authors:

avatar Mohsen Rezaei 1 , * , avatar eskandar rahimi 1 , avatar somayeh bordbar 1 , avatar Sahar Namdar 1

Department of Exercise Physiology, Fars Sciences and Research Branch, Islamic Azad University, Shiraz, Iran
Zahedan Journal of Research in Medical Sciences: Vol.15, issue 5; e92989
published online: November 18, 2012
article type: Short Communication
received: August 22, 2011
accepted: May 06, 2012

how to cite: Rezaei M, rahimi E, bordbar S, Namdar S. The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats. Zahedan J Res Med Sci. 2013;15(5):e92989. 

Abstract

Background: The purpose of this study was to investigate the effects of three sessions of running on a negative slope (eccentric contraction) on changes of the serum levels of aspartate aminotransferase (AST) and alanin aminotransferaze (ALT) in adult male rats.
Materials and Methods: 20 adult male rats were divided randomly into two equal groups (exercise and control). Levels of AST and ALT in both groups were measured in a fasting state, 24 hours before and 24 hours after the last session of training.
Results: Exercise increased the levels of serum AST and ALT enzymes, significantly (p<0.05).
Conclusion: Eccentric exercise, without allowing enough time for returning to the pre-exercise state, leads to the damage of some body organs such as the liver.

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