Evaluation Chemical Composition of Unstimulated Saliva, in Patients with Type I Diabetes Mellitus

Masoomeh Shirzaii; Fathemeh Heidari

Zahedan Journal of Research in Medical Sciences

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Evaluation Chemical Composition of Unstimulated Saliva, in Patients with Type I Diabetes Mellitus

Author(s):

Masoomeh Shirzaii^1,*,

Fathemeh Heidari²

1Department of Oral and Maxillofacial Surgeon, Faculty of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran

2Department of Pathology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 15, issue 1; e93134

Published online:Apr 09, 2012

Article type:Research Article

Received:Aug 21, 2011

Accepted:Oct 13, 2011

How to Cite:Masoomeh ShirzaiiFathemeh HeidariEvaluation Chemical Composition of Unstimulated Saliva, in Patients with Type I Diabetes Mellitus.Zahedan J Res Med Sci.15(1):e93134.

Abstract

Background : Diabetes will result in change in qualitative and quantitative function of saliva. The purpose of the study was to determine the chemical composition (combination) of unstimulated saliva in patients with type I diabetes mellitus.
Materials and Methods : In this case-control study, unstimulated saliva of 25 patients with type I controlled diabetes (20-30 years) and 25 healthy person who matched with the case group in respect of age and gender was gathered and analyzed in order to evaluate the chemical composition of saliva. The data was analyzed using SPSS-18 and independent t-test.
Results : Salivary Ca2+ concentration in diabetic patients was equivalent to 9.2±2.3 mg/dl and in healthy individuals was 9.4±0.7 mg/dl Sodium level (Na+) in diabetics was equal to 1.3±11.8 mg/dl and in healthy individuals was 9.9±2.5 mg/dl Potassium level (K+) in diabetics was equal to 19.5±6.3 mg/dl and in healthy individuals was 15.8±4.4 mg/dl Urea level in diabetics was equal to 19±3.8 mg/dl and in healthy individuals 9.7±1.4 mg/dl and Phosphorus level (P+) in diabetics was equivalent to 12.7±4.6 mg/dl and in healthy individuals was 11±4.8 mg/dl. Salivary K+, Urea, and Na+ concentration in both groups was significantly different (p=0.05).
Conclusion : Chemical composition of saliva in diabetics in relation to healthy individuals was different Urea and Potassium level increased and Sodium level decreased.

Keywords

Saliva

Chemical composition

Diabetes mellitus

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