The Inhibitory Effect of Camellia sinensis Extract on Decreasing Inductive Teratogenicity of Low Frequency Electromagnetic Field in Liver and Spleen of Balb/C Rat Embryo

Javad  Baharara; Naser Mahdavishahri; Saeedeh Zafar-Balanejad; Esmat Kamareh

Zahedan Journal of Research in Medical Sciences

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The Inhibitory Effect of Camellia sinensis Extract on Decreasing Inductive Teratogenicity of Low Frequency Electromagnetic Field in Liver and Spleen of Balb/C Rat Embryo

Author(s):

Javad Baharara^1,*,

Naser Mahdavishahri²,

Saeedeh Zafar-Balanejad³,

Esmat Kamareh⁴

1Department of Animal Developmental Biology, Islamic Azad University, Mashhad branch, Mashhad, Iran

2Department of Biology, Islamic Azad University, Mashhad branch, Mashhad, Iran

3Department of Biology, School of Sciences, Islamic Azad University, Mashhad branch, Mashhad, Iran

4Department of Cell & Developmental Biology, Islamic Azad University, Mashhad Branch, Mashhad, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 14, issue 5; e93439

Published online:Jan 07, 2012

Article type:Research Article

Received:Jul 28, 2011

Accepted:Oct 29, 2011

How to Cite:Javad BahararaNaser MahdavishahriSaeedeh Zafar-BalanejadEsmat KamarehThe Inhibitory Effect of Camellia sinensis Extract on Decreasing Inductive Teratogenicity of Low Frequency Electromagnetic Field in Liver and Spleen of Balb/C Rat Embryo.Zahedan J Res Med Sci.14(5):e93439.

Abstract

Background: Many studies have an emphasis on Reactive Oxygen Species (ROS) formation by electromagnetic field. Camellia sinensis is enriched with antioxidants and the antioxidants can neutralize the effects of ROS. In this study, the effect of Camellia sinensis extract on decreasing the inductive teratogenicity of the electromagnetic field (frequency 50Hz and intensity 50G) in liver and spleen of Balb/C embryonic rat is examined.
Materials and Methods: Twenty-four heads of pregnant female rat (Balb/C) were divided into four groups: control group, experimental test group (off-device), empirical group1 (electromagnetic field 50 Gauss), empirical group2 (treated using Camellia sinensis extract + electromagnetic field 50 Gauss), in this empirical-experimental study. Then, liver and spleen tissue cross sections of 19-day embryos were prepared for histological assessments after weight and Crown-Rump length were measured. Resulting quantitative data was analyzed using ANOVA statistical tests and Tukey test with the significance level (p<0.05).
Results: In examination of tissue sections, mean lymphocyte number of spleen in empirical group 1 showed a significant difference (p=0.001) comparing to the experimental control group, whereas mean lymphocyte number of spleen in empirical group 1 showed a significant difference (p=0.001) comparing to empirical group 2. Mean number of liver hepatocytes empirical samples 2 showed a significant decrease (p=0.004) comparing to the experimental control group, and mean number of liver hepatocytes empirical samples 2 showed a significant decrease (p=0.042) comparing to empirical samples 1.
Conclusion: Consumption of Camellia sinensis could compensate for the inductive impairments in many cells electromagnetic fields, but it is not recommended in pregnancy period cause of changing the number of some cells.

Keywords

Camellia sinensis

Liver

Spleen

Electromagnetic field

Balb/C rat

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