The Relationship between Clinical and Chemical Hyperandrogenism in 14-18-Years- Old Girls

marzieh akbarzadeh; Tahereh Naderi; Mohammad Hossain Dabbaghmanesh; Hamidreza Tabatabaee; Zahra Zareh

Zahedan Journal of Research in Medical Sciences

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The Relationship between Clinical and Chemical Hyperandrogenism in 14-18-Years- Old Girls

Author(s):

marzieh akbarzadeh^1,*,

Tahereh Naderi²,

Mohammad Hossain Dabbaghmanesh³,

Hamidreza Tabatabaee⁴,

Zahra Zareh⁵

1Faculty of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran

2Department of Midwifery, Marvdasht Health Center, Shiraz University of Medical Sciences, Marvdasht, Iran

3Department of Endocrinology, Shiraz Endocrine and Metabolism Research Center, Shiraz, Iran

4Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran

5Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 14, issue 4; e93469

Published online:Jul 27, 2011

Article type:Research Article

Received:May 10, 2011

Accepted:May 25, 2011

How to Cite:marzieh akbarzadehTahereh NaderiMohammad Hossain DabbaghmaneshHamidreza TabatabaeeZahra ZarehThe Relationship between Clinical and Chemical Hyperandrogenism in 14-18-Years- Old Girls.Zahedan J Res Med Sci.14(4):e93469.

Abstract

Background: One of the most common endocrine disorders in women's medicine is the increased androgen and the symptoms of increased androgens in women such as polycystic ovary syndrome. The two main components to diagnose this syndrome are menstrual disorder and clinical or laboratory hyperandrogenism, but other causes should be ruled out in order to confirm the diagnosis. This study aims to examine clinical Hyperandrogenism in female students of 14 to 18 years old in Shiraz in 2010.
Materials and Methods: This cross-sectional study was conducted on 3200 female high school students of 14-18 years old in Shiraz. Data collection tools include questionnaires containing personal details, clinical Hyperandrogenism features (acne, alopecia and hirsutism based on Freeman-Galway scale) and test results. The ultrasound was conducted based on Adams criteria. The data results are analyzed using SPSS-15 software and χ2 and t statistical tests.
Results: In this study, the frequency of hirsutism is 3.2%, prevalence of acne is 5% and alopecia is 4.2%. Mean of free testosterone (1.647±0.835) was higher in the group with hirsutism, acne and alopecia. Independent t-test showed no significant relationship between patients with hirsutism, acne and alopecia and non-affected people in terms of mean of total testosterone and free testosterone. However, there is a significant relationship between people with acne and hirsutism and polycystic ovary compared with those with acne and hirsutism and those without polycystic ovary (p >0.05).
Conclusion: This study indicated that clinical and chemical hyperandrogenism can be a criterion to diagnose with polycystic ovary syndrome, but ultrasound was not helpful.

Keywords

Hyperandrogenism

Polycystic Ovary Syndrome

Girls

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