Refractive Error and Fixation Conditions of Infants Born by Assisted Reproductive Techniques

authors:

avatar Ebrahim Jafarzadehpur 1 , * , avatar Ramin Mozafari-Kermani 2 , avatar Alireza Mohhamadi 3 , avatar Mohammad Reza Nateghi 2 , avatar Seyed Abolhassan Shahzadeh Fazeli 4 , avatar Hamid Gurabi 5

Department of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran
Department of Child Health and Development Research (CDR), Tehran University of Medical Sciences Branch of Academic Center for Education, Culture and Research (ACECR), Tehran, Iran
Noor Ophthalmology Research Center, CDR of Tehran University of Medical Sciences Branch of ACECR, Tehran, Iran
Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
Tehran University of Medical Sciences Branch of Academic Center for Education, Culture and Research (ACECR), Tehran, Iran

How To Cite Jafarzadehpur E, Mozafari-Kermani R, Mohhamadi A, Nateghi M R, Shahzadeh Fazeli S A , et al. Refractive Error and Fixation Conditions of Infants Born by Assisted Reproductive Techniques. Zahedan J Res Med Sci. 2012;14(4):e93470. 

Abstract

Background: The objective of this study is to evaluate the refractive error and oculomotor conditions of infants born  by assisted reproductive techniques (ART) in patients referring to Royan Institute as well as Child Health and Development Center.
Materials and Methods: In this cross-sectional study, 270 ART-exposed infants aged less than 9 months were tested by retinoscopy, fixation conditions, Hirschberg and Doll's eye maneuver.
Results: The average refractive error of these infants shows hyperopic Shift +0.9±1.1 D. The average astigmatism recorded in these infants is -0.6±0.6D. The prevalence of refractive errors in these infants is myopia 6%, hyperopia 85% and emmetropia 9%. Impairment of fixation conditions, Hirschberg test and Doll's eye maneuver was respectively observed in 20.4, 1.4 and 3.7% of the studied infants.
Conclusion: Given the sensitivities in the visual system development process and critical period which is important for every infant in the very first months of birth, it seems that visual-ocular studies are more important in ART-exposed infants who were exposed to different factors until their birth. The results of refractive errors, fixation conditions, Hirschberg test and Doll’s head maneuver which was conducted in this study for these infants reveal that, it is likely that visual impairment in these infants is higher than the results of foreign studies. However, lack of access to population studies in infants below 1 year of age in Iran necessitates more extensive studies and follow-ups of vision of ART-exposed infants more seriously.

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