The effect of two dosage of BCAA supplementation on wrestlers’ serum indexes on cellular injury

authors:

avatar Ramin Amirsasan 1 , avatar Saeed Nikookheslat 1 , avatar Vahid Sari-Sarraf 1 , avatar Batoorak Kaveh 2 , avatar Amir Letafatkar 3 , *

Assistant Professor of Sport Physiology, School of Physical Education, Tabriz University, Tabriz, Iran.
MSc of Sport Physiology, School of Physical Education, Tabriz University, Tabriz, Iran.
PhD Student of Sport Injury and Corrective Exercise, School of Physical Education, Tehran university, Tehran, Iran.
Zahedan Journal of Research in Medical Sciences: Vol.13, issue 8; e93769
published online: May 27, 2011
article type: Research Article
received: October 25, 2010
accepted: November 24, 2010

how to cite: Amirsasan R, Nikookheslat S, Sari-Sarraf V, Kaveh B, Letafatkar A . The effect of two dosage of BCAA supplementation on wrestlers’ serum indexes on cellular injury. Zahedan J Res Med Sci. 2012;13(8):e93769. 

Abstract

Background: A few studies were done to examine the effect of different dosage of branched-chain amino acid (BCAA) supplementation on serum indexes of muscle injury in wrestlers. The purpose of this research was to compare the effects of two dosage of branched-chain amino acid supplementation on muscle serumic damage indexes after heavy resistance exercise in wrestlers.
Materials and Method: Twenty-nine young wrestlers were randomly selected and divided into three groups. All subjects were participated in heavy resistance exercise (3 sets, 10 repetitions, 80% 1RM). The BCAA was given at doses of 210 and 450 mg/kg for supplemental groups 1 and 2 respectively, 30 minutes before and after to exercise test and dextrin was given at dose of 210 mg/kg for control group. To identify enzymes activity (IU/L), venous blood samples were obtained 30 min prior to exercise and at 24 and 48 hrs after exercise. Data were statistically analyzed using ANOVA with repeated measures and Bonfferoni post hoc test (p≥ 0.05).
Results: Based on this study results, CPK, LDH, CPKMB activity were significantly increased (p<0.05) in all groups. CPK, LDH, CPKMB indexes having the highest activity in the control group, but there were no significant differences between all groups.
Conclusion: These results provide evidence that the use of two different dosage of BCAA could not decrease muscle damage associated with heavy resistance exercise.

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