The effect of two dosage of BCAA supplementation on wrestlers’ serum indexes on cellular injury

Ramin Amirsasan; Saeed Nikookheslat; Vahid Sari-Sarraf; Batoorak Kaveh; Amir  Letafatkar

Zahedan Journal of Research in Medical Sciences

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The effect of two dosage of BCAA supplementation on wrestlers’ serum indexes on cellular injury

Author(s):

Ramin Amirsasan¹,

Saeed Nikookheslat¹,

Vahid Sari-Sarraf¹,

Batoorak Kaveh²,

Amir Letafatkar^3,*

1Assistant Professor of Sport Physiology, School of Physical Education, Tabriz University, Tabriz, Iran.

2MSc of Sport Physiology, School of Physical Education, Tabriz University, Tabriz, Iran.

3PhD Student of Sport Injury and Corrective Exercise, School of Physical Education, Tehran university, Tehran, Iran.

Zahedan Journal of Research in Medical Sciences:Vol. 13, issue 8; e93769

Published online:May 27, 2011

Article type:Research Article

Received:Oct 25, 2010

Accepted:Nov 24, 2010

How to Cite:Ramin AmirsasanSaeed NikookheslatVahid Sari-SarrafBatoorak KavehAmir LetafatkarThe effect of two dosage of BCAA supplementation on wrestlers’ serum indexes on cellular injury.Zahedan J Res Med Sci.13(8):e93769.

Abstract

Background: A few studies were done to examine the effect of different dosage of branched-chain amino acid (BCAA) supplementation on serum indexes of muscle injury in wrestlers. The purpose of this research was to compare the effects of two dosage of branched-chain amino acid supplementation on muscle serumic damage indexes after heavy resistance exercise in wrestlers.

Materials and Method: Twenty-nine young wrestlers were randomly selected and divided into three groups. All subjects were participated in heavy resistance exercise (3 sets, 10 repetitions, 80% 1RM). The BCAA was given at doses of 210 and 450mg/kg for supplemental groups 1 and 2 respectively, 30 minutes before and after to exercise test and dextrin was given at dose of 210 mg/kg for control group. To identify enzymes activity (IU/L), venous blood samples were obtained 30 min prior to exercise and at 24 and 48 hrs after exercise. Data were statistically analyzed using ANOVA with repeated measures and Bonfferoni post hoc test (p≥ 0.05).

Results: Based on this study results, CPK, LDH, CPK_MB activity were significantly increased (p<0.05) in all groups. CPK, LDH, CPK_MB indexes having the highest activity in the control group, but there were no significant differences between all groups.

Conclusion: These results provide evidence that the use of two different dosage of BCAA could not decrease muscle damage associated with heavy resistance exercise.

Keywords

BCAA

muscle damage

exercise

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