A comparative study of different doses of dexamethasone on postoperative nausea and vomiting following anesthesia for cataract surgery

Shahram Amini; Assadallah Kaykhaee; Fariba Azmoon

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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A comparative study of different doses of dexamethasone on postoperative nausea and vomiting following anesthesia for cataract surgery

Author(s):

Shahram Amini^1,*,

Assadallah Kaykhaee²,

Fariba Azmoon³

1Associate Professor of Anesthesiology, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.

2Instructor Professor of Anesthesiology, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.

3General Physician, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran. Please

Zahedan Journal of Research in Medical Sciences:Vol. 13, issue 5; e93906

Published online:May 26, 2011

Article type:Research Article

Received:Sep 12, 2010

Accepted:Oct 12, 2010

How to Cite:Shahram AminiAssadallah KaykhaeeFariba AzmoonA comparative study of different doses of dexamethasone on postoperative nausea and vomiting following anesthesia for cataract surgery.Zahedan J Res Med Sci.13(5):e93906.

Abstract

Background: Postoperative nausea (PONV) and vomiting is the most common complication after surgery that might prolong discharge time and cause some morbidity. Dexamethasone can effectively reduce PONV. This study was conducted to evaluate the efficacy of different doses of dexamethasone on PONV.

Materials and Method: In a double blind clinical study we investigated the efficacy of three doses of dexamethasone (0.1mg/kg‚0.3mg/kg‚0.5mg /kg) in ASA class I or II patients randomly allocated into three groups for cataract surgery. The patients were tracked for the frequency of development of PONV in the recovery room and the ward and were compared accordingly.

Results: The patients were similar with respect to demographic parameters and duration of anesthesia. PONV occurred in 4%‚ 4% and 6% in patients in the 0.1mg/kg‚ 0.3mg/kg and 0.5mg/kg group, respectively (p= 0.577)

Conclusion: We concluded that lower doses of dexamethasone could reduce PONV as much as higher doses. We suggest the lowest dose to reduce both the cost and side effects.

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