Seroepidemiologic assessment of Hepatitis E virus in women of reproductive age, Gorgan

1Associated Professor, Dept. of Virology, Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences and Health Services, Gorgan, Iran.

2General Practitioner, Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences and Health Services, Gorgan, Iran.

3Assistant Professor, Dept. of Virology, Golestan Research Center of Infectious Diseases, Golestan University of Medical Sciences and Health Services, Gorgan, Iran.

Zahedan Journal of Research in Medical Sciences:Vol. 12, issue 1; e94352

Published online:Jan 14, 2010

Article type:Brief Report

Received:Apr 18, 2009

Accepted:Nov 15, 2009

How to Cite:Abdolvahab Moradi Sima BesharatMohammad Mehdi MinaiifarGholamreza RoshandelAlijan TabaraiiSeroepidemiologic assessment of Hepatitis E virus in women of reproductive age, Gorgan.Zahedan J Res Med Sci.12(1):e94352.

Abstract

Background: Hepatitis E virus can be disseminated oral-fecally and its fulminant form mortality rate maybe up to 20% in the third trimester of pregnancy. This study aimed to assess the sero-epidemiology of HEV in women of reproductive age in Gorgan, Iran.

Materials and m ethods: In this cross-sectional descriptive study, 1200 women ages between 17-45 years were recruited from laboratories and health care systems of Gorgan. Demographic data was recorded in the checklists. ELISA method (DIAPRO) was done to evaluate the anti-HEV antibody. Data were entered into SPSS-13 software for analysis by Chi-squared and Fisher exact test.

Results: Mean ( ± SD) age of the cases was 27.41 ( ±6.33). Among 1200 subjects, 76(6.3%) cases had positive anti-HEV antibodies. Age and ethnicity had a significant relationship with HEV (p-value<0.05), but no significant relationship was seen between other variables.

Conclusions: According to our results and due to higher positive cases in 30-40 years-old women, more researches especially in pregnant women are suggested.

Keywords

General Practitioner

Golestan Research Center of Gastroenterology and Hepatology

Golestan University of Medical Sciences and Health Services

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