The Alterations of Serum Cortisol Level and Blood Count in Male Rats after a Short Term Exposure to Burned Radioactive Lantern Mantle Powder

S M Javad Mortazavi; Majid Asiabanha; Mohammad Reza Rahmani; Mohsen Rezaei; Vahid Pooladvand

Zahedan Journal of Research in Medical Sciences

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The Alterations of Serum Cortisol Level and Blood Count in Male Rats after a Short Term Exposure to Burned Radioactive Lantern Mantle Powder

Author(s):

S M Javad Mortazavi^1,*,

Majid Asiabanha²,

Mohammad Reza Rahmani³,

Mohsen Rezaei⁴,

Vahid Pooladvand²

1Associate Prof, The Center for Radiological Sciences Research and Dept of Medical Physics, Shiraz University of Medical Sciences, Shiraz, Iran.

2Master Student, Dept of Biochemistry-Medical Physics, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

3Instructor, Dept of Physiology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

4Associate Prof, Dept of Social Medicine, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Zahedan Journal of Research in Medical Sciences:Vol. 11, issue 4; e94374

Published online:Dec 20, 2009

Article type:Research Article

Received:Jan 18, 2009

Accepted:Nov 15, 2009

How to Cite:S M Javad MortazaviMajid AsiabanhaMohammad Reza RahmaniMohsen RezaeiVahid PooladvandThe Alterations of Serum Cortisol Level and Blood Count in Male Rats after a Short Term Exposure to Burned Radioactive Lantern Mantle Powder.Zahedan J Res Med Sci.11(4):e94374.

Abstract

Background: Most lantern mantles contain low levels of radioactive thorium. Although radioactive lantern mantles present a minimal radiation health hazard, it is generally believed when inhaled or ingested, it can be dangerous. The purpose of this study was to assess the effect of short term exposure to radioactive lantern mantle on serum cortisol level and blood count.

Materials and Methods : This experimental study was conducted in 2007-2009 in the school of medicine of Rafsanjan University of Medical Sciences. Twenty eight rats were divided randomly into two groups of 14 animals each. The first group was exposed to 600 mg burned radioactive lantern mantle powder (activity of 800Bq) for 24 hours and inhaled radon released from mantles. The second group was exposed to non-radioactive lantern mantle powder at the same interval. Paired t-test was used to evaluate the difference in the means of cortisol and blood cell count in both groups. P<0.05 was considered as the significance level.

Results: Short term exposure of animals to radioactive lantern mantle powder led to a statistically significant decreased cortisol level, while no statistically significant decrease was found in animals that were exposed to non-radioactive mantle powder. Furthermore, a significant reduction was shown in post-exposure counts of WBC in the case group.

Conclusions: Despite alteration of serum cortisol level, this study could not show stimulatory effects in some blood counts.

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