Abstract
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. But
information regarding CRC in Iran is limited; the aim of this study was to investigate the
epidemiologic features of CRC in Iran, using 6-year data from cancer registry.
Materials and Methods: This survey was a descriptive-analytic study conducted on 1138
colorectal cancer patients who registered in Cancer Registry Center of Research Center for
Gastroenterology and Liver Disease, Tehran, Iran. These data were gathered through interview
and pathology reports recorded in cancer registry forms. Data analysis was performed by
descriptive and univariate methods.
Results: Of 1138 patients, 696 cases were male. There was no significant difference between
males and females regarding age at diagnosis. 400 patients (35.1%) had a family history of cancer.
The most common histology type of tumor was adenocarcinoma, NOS. In most cases (39.1%) tumor
grading was well differentiated and there was no significant difference between males and females.
Conclusion: Colorectal cancer is a disease with nonspecific symptoms. Family history of
cancer was evident in 35.1% of our cases and also 42.9% of patients were below the age of 50
years old, suggesting that genetic factors may play an important role in the development of this
disease in our country.
information regarding CRC in Iran is limited; the aim of this study was to investigate the
epidemiologic features of CRC in Iran, using 6-year data from cancer registry.
Materials and Methods: This survey was a descriptive-analytic study conducted on 1138
colorectal cancer patients who registered in Cancer Registry Center of Research Center for
Gastroenterology and Liver Disease, Tehran, Iran. These data were gathered through interview
and pathology reports recorded in cancer registry forms. Data analysis was performed by
descriptive and univariate methods.
Results: Of 1138 patients, 696 cases were male. There was no significant difference between
males and females regarding age at diagnosis. 400 patients (35.1%) had a family history of cancer.
The most common histology type of tumor was adenocarcinoma, NOS. In most cases (39.1%) tumor
grading was well differentiated and there was no significant difference between males and females.
Conclusion: Colorectal cancer is a disease with nonspecific symptoms. Family history of
cancer was evident in 35.1% of our cases and also 42.9% of patients were below the age of 50
years old, suggesting that genetic factors may play an important role in the development of this
disease in our country.
Keywords
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Copyright
© 2007, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0) (https://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.