Effects of oral clonidine as pre-medication on blood pressure in patients under spinal anesthesia

authors:

avatar Shahram Borjian Boroojeny 1 , * , avatar SA Keykhaei 1 , avatar GH Sargazi 1 , avatar Ali Navidian 2

Anesthesia Dept, Faculty of Medicine, Zahedan University of Medical Science and health services, Zahedan, Iran.
Anesthesia Dept, Paramedical School, Zahedan University of Medical Science and health services, Zahedan, Iran.

how to cite: Borjian Boroojeny S, Keykhaei S, Sargazi G, Navidian A. Effects of oral clonidine as pre-medication on blood pressure in patients under spinal anesthesia. Zahedan J Res Med Sci. 2006;8(2):e94896. 

Abstract

We have studied the effect of oral clonidine on Blood Pressure of the Patients under spinal
anesthesia. For minor to moderate surgeries at Khatam-ul-anbia Hospital of Zahedan –Iran in
1380(2001).
In this double –blinded , prospective , randomized study involving 50 patients who that divided
in two 25-patients groups and the first groups reciveved oral clonidine 2 μg/kg drug 90 min prespinal
anesthesia and the other group did not resived any drugs.
12% of group 1 patients had diastolic and systolic hypotension but at group 2 , 24% had systolic
hypotension and 16% had diastolic hypotension after 10 min interval of spinal anesthesia. But there
were no statistical difference between the two groups.
Implications:
Oral clonidine as premedication has no any effect on the blood pressure following spinal
anesthesia, so we can use oral clonidine as premedication for its benefits.

Fulltext

We have studied the effect of oral clonidine on Blood Pressure of the Patients under spinal
anesthesia. For minor to moderate surgeries at Khatam-ul-anbia Hospital of Zahedan –Iran in
1380(2001).
In this double –blinded , prospective , randomized study involving 50 patients who that divided
in two 25-patients groups and the first groups reciveved oral clonidine 2 μg/kg drug 90 min prespinal
anesthesia and the other group did not resived any drugs.
12% of group 1 patients had diastolic and systolic hypotension but at group 2 , 24% had systolic
hypotension and 16% had diastolic hypotension after 10 min interval of spinal anesthesia. But there
were no statistical difference between the two groups.
Implications:
Oral clonidine as premedication has no any effect on the blood pressure following spinal
anesthesia, so we can use oral clonidine as premedication for its benefits.

References

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