Non-HDL-C versus LDL-C for screening of hyperlipidemic patients

AA Rakhshani; Masoud Salehi

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

Current Issue All Issues In Press Articles Accepted Manuscripts Search

Journal Information Boards and Committees Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support Reviewer and AE Registration Form

APC

Authors Guide Submit Manuscript

Non-HDL-C versus LDL-C for screening of hyperlipidemic patients

Author(s):

AA Rakhshani^1,*,

Masoud Salehi²

1Cardiologist Dept, Paramedical School, Zahedan University of Medical Science and health services, Zahedan, Iran.

2Tropical and Infectious Diseases Dept, Faculty of Medicine, Zahedan University of Medical Sciences and health services, Zahedan, Iran.

Zahedan Journal of Research in Medical Sciences:Vol. 8, issue 2; e94899

Published online:Jun 06, 2006

Article type:Research Article

Received:Feb 10, 2005

Accepted:May 16, 2006

How to Cite:AA RakhshaniMasoud SalehiNon-HDL-C versus LDL-C for screening of hyperlipidemic patients.Zahedan J Res Med Sci.8(2):e94899.

Abstract

Background: Measurement of the plasma lipids is an essential component of prophylactic
medicine. The current screening test for prediction of cardiovascular complications due to
hyperlipidemia is LDL-C measurement through Friedwald formula. This test becomes progressively
less accurate as plasma TG increases. The test is inapplicable in TG over 400. The measurement of
non-HDL-C versus LDL-C in screening of hyperlipidemic patients is the aim of this study.
Materials and Methods: In a descriptive analytic study we divided 1000 patients (20-60 years old)
who referred to two laboratories in Zahedan Into five groups according to their TG levels. HDL-C
(with Friedwald Formula), non-HDL-C, the correlation between HDL-C and plasma cholesterol
level, the correlation between non-HDL-C and plasma cholesterol level were determined in each
group.
Results: The findings revealed that the correlation between LDL-C and plasma cholesterol level
decreases as TG level increases. At TG levels less than 400 mg/dl the correlation between LDL and
non-HDL was not significant but was at TG levels over 400.
Conclusion: It is inferred that we can use non-HDL instead of LDL-C (at any TG level) in order
to screening of hyperlipidemic patients without fasting. It is still necessary to measure TG level for
appropriate drug selection.

Keywords

Fulltext

The full text of this article is available on the PDF file.

References

1.
The References of this article are available on the PDF file.

comments