How is the Agreement of DXA and QUS of Phalanx in Defining Osteoporosis in Healthy Postmenopausal Women

authors:

avatar m Sedaghat 1 , * , avatar z Hamidi 2 , avatar a Soltani 2 , avatar A Hossein Nezhad 2 , avatar E Rahimi 2 , avatar b Larijani 2

Social medical, faculty of medicine, Tehran University of Medical Sciences and health services, Tehran, Iran.
Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences and health services, Tehran, Iran.

how to cite: Sedaghat M, Hamidi Z, Soltani A, Hossein Nezhad A, Rahimi E, et al. How is the Agreement of DXA and QUS of Phalanx in Defining Osteoporosis in Healthy Postmenopausal Women. Zahedan J Res Med Sci. 2003;5(2):e95150. 

Abstract

QUS (Quantitative Ultrasound) of phalanx is a noninvasive, inexpensive and portable
method for bone mineral densitometry. It seems it measures some other parameters in
addition to BMD, like elasticity and micro architecture. This study designed to determine
the agreement of DXA and QUS of phalanx in Defining Osteoporosis in Healthy
Postmenopausal Women Using DXA, BMD of lumbar spine and
Different areas of left femur and using QUS, BMD of phalanx was measured in 180
healthy postmenopausal women. The diagnostic agreement between the two techniques in
identifying osteoporosis was assessed using kappa scores. According to the World Health
Organization definitions, Osteoporosis found in 28.8% of cases with DXA method (18.3%
in L2-L4 and 3.9%-7.8% in different region of femur) and in 28.9% of cases with Phalanx
ultrasonography). Kappa score was 0.317 for lumbar region and 0.036-0.068 for
different regions femur.
Results of this study show a weak to moderate agreement of two methods in diagnosis
of osteoporosis. It means QUS of phalanx can’t be used as a replacement for DXA
method but could be used as a screening method for finding osteoporotic cases.

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