Archives of Clinical Infectious Diseases
Infectious Diseases and Tropical Medicine Research Center, SBUMS
Authors
Brucellosis is a zoonotic, chronic and infectious disease, which is caused by bacteria of genus Brucella. The present study investigated exactly what species and biovars of Brucella are responsible for brucellosis in Iran.
The various species of Brucella were mostly being isolated from suspected specimens of animal fetus, placenta, vaginal swab, lymph nodes, milk, and human blood and bone marrow cultures. A total of 618 strains of B. abortus and 2413 strains of B. melitensis have been subjected to the identification procedures.
Of 3031 isolates, 618 and 2413 were B. abortus and B. melitensis, respectively. Strains of B. abortus were isolated from cattle (612 cases) and sheep (6 cases). These isolates were biovars 1 (70 cases), 2 (1 case), 3 (511 cases), 4 (1 case), 5 (30 cases) and 9 (5 cases). Biovar 3 is considered as the endemic one and biovars 1 and 5 are the most prevalent. B. melitensis strains were isolated from sheep and goats (1717 cases), cattle (109 cases), camel (5 cases), dogs (4 cases) and human beings (497 cases). These isolates were biovars 1 (2102 cases), 2 (205 cases) and 3 (106 cases). B. suis, B. neotomae, B. ovis and B. canis were not isolated.
In many regions of Iran B. abortus biovar 3 still remains the dominant one, however, for B. melitensis biovar 1 is the most prevalent one.
© 2008, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Mokhtari A, Binandeh H, Rahimi Junqani R. Brucella abortus Emerges as Predominant Brucellosis Agent in Golestan Province: A Molecular Detection Study in Suspected Human Cases. J Microbiota. 2025;2(2):e162136. doi: https://doi.org/10.5812/jmb-162136
Mirnejad R, Mohammadi M, Majdi A, Taghizoghi N, Piranfar V. Molecular Typing of Brucella melitensis and B. abortus From Human Blood Samples Using PCR-RFLP Method. Jundishapur J Microbiol. 2013;6(6):e7197. doi: https://doi.org/10.5812/jjm.7197
Mirnejad R, Vahdati AR, Ahmadi A, Mortazavi SM, Piranfar V. Comparison of Culture and Multiplex PCR Technique for Detection of Brucella abortus and Brucella melitensis from Human Blood Samples. Zahedan J Res Med Sci. 2013;15(12):e4325. doi:
Bahmani N, Hashemi SH, Arabestani MR, Mirnejad R, Masjedianjazi F, et al. Molecular Typing of Brucella Species Isolated from Humans and Animals Using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Technique. Arch Clin Infect Dis. 2018;13(2):e59305. doi: https://doi.org/10.5812/archcid.59305
Keyvanfar A, Sali S, Zamani A. Epidemiology, Clinical and Laboratory Manifestations, and Outcomes of Brucellosis Among 104 Patients in Referral Hospitals of Tehran, Iran. Arch Clin Infect Dis. 2021;16(2):e111546. doi: https://doi.org/10.5812/archcid.111546
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